Search results for CRISPR-Cas9

Molecular & Computational biology Jun 9, 2025

CRISPR-based technology leads to discovery of complex multigenic traits in tomato plants

Researchers from Tel Aviv University have developed a genetic editing method tailored to crop plants, which has influenced various traits in tomato plants, including the taste and shape of the fruit. The researchers believe ...

Biotechnology Jun 4, 2025

Manipulating DNA repair proteins to improve gene editing outcomes

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation. The treatment was created using a form of ...

Biotechnology May 29, 2025

Study reveals factors that drive efficient, precise editing and hidden DNA repair

Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR genome editing—accurately predicting guide RNA (gRNA) activity.

Bio & Medicine May 22, 2025

Gene delivery system uses nanostraws and electrical pulses to engineer cancer-fighting immune cells

Researchers at the National University of Singapore (NUS) have developed a scalable, non-viral technology that efficiently delivers genetic material into human immune cells. The platform, called Nanostraw Electro-actuated ...

Biotechnology May 21, 2025

Organoid research platform allows investigation of antiviral immunity in bats

Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease outcomes these viruses ...

Cell & Microbiology May 21, 2025

Mapping ATP's journey: Key protein identified as gateway for energy delivery into endoplasmic reticulum

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy transport could affect ...

Cell & Microbiology May 16, 2025

Scientists identify new defense mechanism in CRISPR system

Every living creature on Earth needs to protect itself from things that would do it harm. Bacteria are no different. And despite their relative simplicity, they deploy remarkably savvy defensive strategies against viral invaders. ...

Biotechnology May 15, 2025

Advanced gene editor enables more precise insertion of complete genes

Ask scientists which gene-editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia University Vagelos College of ...

Biotechnology May 15, 2025

Cas9 ancestor engineered into a compact genome editing tool

Scientists at the McGovern Institute and the Broad Institute of MIT and Harvard have reengineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA. The engineered protein, ...

Biotechnology May 8, 2025

The first genetic editing in spiders with CRISPR‐Cas yields colorful silk

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 gene-editing tool to spiders. Following the genetic modification, the spiders produced red fluorescent ...

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