Search results for CRISPR-Cas9

Biotechnology Jul 1, 2025

Web-based tool improves CRISPR accuracy by identifying off-target effects across genetic variations

Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about unintended edits at off-target DNA sites. These off-target effects can cause harmful mutations and ...

Cell & Microbiology Jul 1, 2025

Unique cell receptor interactions found essential for embryo body plan formation

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells communicate with one another during this process through cell-surface receptors, which interact ...

Bio & Medicine Jun 30, 2025

Slowing RNA drug transport inside cells can boost effectiveness for genetic diseases

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of RNA-based drugs can significantly enhance their effectiveness. These promising therapeutics are currently ...

Plants & Animals Jun 27, 2025

Previously unknown SCEP3 protein found essential for plant chromosome mixing in meiosis

Researchers at the IPK Leibniz Institute have discovered a previously unknown protein that is central to plant reproduction. The protein SCEP3 enables plants to mix and precisely distribute their chromosomes—carriers of genetic ...

Molecular & Computational biology Jun 16, 2025

RNA has newly identified role: Repairing serious DNA damage to maintain the genome

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double helix.

Molecular & Computational biology Jun 12, 2025

Key translational mechanism may help prevent crop losses from early sprouting

A research team led by Prof. Cao Xiaofeng from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences has uncovered a key translational regulatory mechanism governing the seed-to-seedling ...

Biotechnology Jun 11, 2025

Boosting precision gene editing: Autophagy shifts DNA repair toward homologous recombination

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly enhance the low efficiency ...

Biotechnology Jun 10, 2025

Genome engineers expand the reach and precision of human gene editing

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field. While existing editing technologies can alter or delete ...

Biotechnology Jun 10, 2025

Scientists successfully edit oat DNA using for first time, enabling climate-resilient crops

For the first time, scientists have successfully edited oat DNA, a breakthrough that could accelerate the development of oats with more fiber, higher yields, and greater resilience to climate change.

Plants & Animals Jun 10, 2025

How do axolotls regenerate limbs and organs? A researcher has started to uncover their secret

Axolotls, with their signature smiles and pink gills, are the celebrities of the salamander world. But they are more than just cute: They might also hold the secret to regenerating human limbs.

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