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Our bodies comprise different tissues and organs, which are composed of many cells that must adhere to form functional higher order structures. This adherence is facilitated by specialized proteins called cell–cell adhesion ...
An advanced imaging technique reveals new structural details of S-DNA, ladder-like DNA that forms when the molecule experiences extreme tension. This work conducted at Sandia National Laboratories and Vrije University in ...
(PhysOrg.com) -- Far-field optical nanoscopy methods, especially STED (stimulated emission depletion), pose very strict and, at times, contradictory requirements on the utilized fluorescent markers. Photostable fluorescent ...
Atomic force microscopy (AFM) offers a method for label-free imaging of nanoscale biomolecular dynamics to solve biological questions that cannot be addressed via other bioimaging methods including fluorescence and scanning ...
Scientists at Weill Cornell Medicine have developed a computational technique that greatly increases the resolution of atomic force microscopy, a specialized type of microscope that "feels" the atoms at a surface. The method ...
Modifying a protein from a plant much favored by science, researchers at the University of California, San Diego School of Medicine and colleagues have created a new type of genetic tag visible under an electron microscope, ...
Tumor metastatic sentinel lymph nodes are difficult to distinguish from normal or inflamed lymph nodes (Inf-LN). Researchers designed a dual-targeting nanoparticle 5K-HA-HPPS for fluorescent/photoacoustic imaging of sentinel ...
National University of Singapore researchers have developed a new generation of near infra-red (NIR)-emitting nanoprobes for super-resolution imaging in deep tissues. These nanoprobes are based on lanthanide-doped nanomaterials ...
A fluorescent imaging probe developed by A*STAR researchers has allowed scientists for the first time to visualize the detailed three-dimensional distribution of alpha cells in the pancreas of mice1. The probe could enhance ...
Scientists have married two of today's most powerful microscopy techniques to make images that pinpoint, for the first time, the identities and precise locations of individual proteins within the detailed context of bacterial ...
