PNP editing is emerging as a versatile and programmable tool for site-specific DNA manipulations. An innovative genome-editing technique could enhance the delivery, specificity and targeting of gene-modifying tools for treatments.
Organisms across the globe are facing unprecedented levels of stress from climate change, habitat destruction, and many other human-driven changes to the environment. Predicting and mitigating the effects of this increasing ...
Ion channels are structures within cell membranes that enable specific ions to travel to and from the cell. Such transfer is essential for a variety of physiological processes such as muscle cell contraction and nerve excitation. ...
A new liquid metal combination is shaping up as a potential secret weapon in the global fight against antimicrobial resistance, which is already rendering some antibiotic medications powerless against 'superbugs'.
In the never-ending arms race between bacteriophages and their prokaryotic hosts, prokaryotes have developed diverse defense systems to fend off phage invasions. These defense systems include the restriction-modification ...
Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool.
Most prokaryotes have never been isolated in pure culture and cannot be named under the International Code of Nomenclature of Prokaryotes (ICNP). However, many studies have described uncultured bacteria and archaea though ...
Transmembrane signaling involves sensing and communicating with the extracellular environment. Part of the transmembrane signaling is a process known as autoproteolysis, which is key in different functions of a cell.
A Geobacter bacteria isolated from a contaminated ditch in Oklahoma has an unusual appendage—a long extracellular nanowire that can conduct electricity. The electron transport chain in this nanowire carries electrons from ...
A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes—organisms that include ...
