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Space Exploration May 8, 2019

Tissue chip headed to International Space Station for osteoarthritis study

On May 4, a National Center for Advancing Translational Sciences (NCATS)-supported tissue-chip system with direct clinical applications to health conditions here on Earth was launched on the SpaceX CRS 17/Falcon 9 rocket.

Cell & Microbiology Apr 11, 2019

In mice, eliminating damaged mitochondria alleviates chronic inflammatory disease

Inflammation is a balanced physiological response—the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases. To ...

General Physics Dec 27, 2018

Nucleus-specific X-ray stain for 3-D virtual histology

Histology is used to identify structural details of tissue at the microscale in the pathology lab, but analyses remain two-dimensional (2D) as they are limited to the same plane. Nondestructive 3D technologies including X-ray ...

Engineering Dec 20, 2018

Micropores let oxygen and nutrients inside biofabricated tissues

Micropores in fabricated tissues such as bone and cartilage allow nutrient and oxygen diffusion into the core, and this novel approach may eventually allow lab-grown tissue to contain blood vessels, according to a team of ...

Archaeology Dec 6, 2018

The medieval mystery of the booted man in the mud

A mysterious male skeleton, lying face-down deep in the Thames mud, with a pair of in-situ thigh-high leather boots has been discovered by our archaeologists working on one of the sites being used to build London's super ...

Plants & Animals Oct 30, 2018

New gene-therapy eases chronic pain in dogs—human trials underway

When Shane the therapy dog was hit by a Jeep, life changed for him and his guardian Taryn Sargent.

Biochemistry Oct 30, 2018

The 10-foot-tall microscopes helping combat world's worst diseases

The century old mission to understand how the proteins responsible for amyloid-based diseases such as Alzheimer's, Huntingdon's and Parkinson's work has taken major steps forward in the last 12 months, thanks to a revolution ...

Cell & Microbiology Oct 24, 2018

Antibiotic explorers: The intricate quest to discover where tetracyclines go in human cells

We know that antibiotics treat bacterial infections. We also know why they work. Tetracycline antibiotics, for example, stop bacteria from making protein. Like a boot on a wheel, the drugs bind to the bacterial cell's ribosome—where ...

Biotechnology Aug 9, 2018

Genes drive aging, making normal processes damaging

Ageing in worms mainly results from the direct action of genes and not from random wear and tear or loss of function, and the same is likely to be true in humans, according to research by UCL, Lancaster University and Queen ...

Plants & Animals Jun 6, 2018

Obese dogs could have similar 'personality' traits to overweight humans – new study

We're all told we need to eat healthier and exercise more to combat obesity, but did you know that there's also an obesity epidemic among pets, at least in the West? Between 39% and 59% of pet dogs in Europe, Australia and ...

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