Search results for DNA nanoswitches

Bio & Medicine Oct 21, 2021

Fingerprinting proteins with force opens a new avenue for single-molecule proteomics

As scientists have probed the mysteries of life down to smaller and smaller scales, they have invented tools to help them understand what they observe. Determining the identity of DNA and RNA molecules has now become commonplace ...

Bio & Medicine May 10, 2021

Foldable, organic and easily broken down: Why DNA is the material of choice for nanorobots

Only in cancer medicine do clinicians aim to attack and kill legions of a patient's own cells. But healthy bystander cells often get caught in deadly crossfire, which is why cancer treatments can cause severe side effects ...

Bio & Medicine Mar 26, 2019

Cellular microRNA detection with miRacles

MicroRNAs (miRNAs) are short noncoding regulatory RNAs that can repress gene expression post-transcriptionally and are therefore increasingly used as biomarkers of disease. Detecting miRNAs can be arduous and expensive as ...

Bio & Medicine Sep 11, 2017

To improve health monitoring, simply trip the 'nanoswitch'

Engineered strands of DNA—nanoscale tools called "nanoswitches"—could be the key to faster, easier, cheaper and more sensitive tests that can enable high-fidelity detection of biomarkers indicating the presence of different ...

Bio & Medicine Mar 17, 2016

Democratizing high-throughput single molecule force analysis

From the tension of contracting muscle fibers to hydrodynamic stresses within flowing blood, molecules within our bodies are subject to a wide variety of mechanical forces that directly influence their form and function. ...

Analytical Chemistry Oct 7, 2015

Detecting HIV diagnostic antibodies with DNA nanomachines

New research may revolutionize the slow, cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and auto-immune diseases such as rheumatoid arthritis and HIV. An international ...

Bio & Medicine Mar 2, 2015

New nanodevice defeats drug resistance

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that ...

Bio & Medicine Jan 30, 2015

DNA nanoswitches reveal how life's molecules connect

A complex interplay of molecular components governs almost all aspects of biological sciences - healthy organism development, disease progression, and drug efficacy are all dependent on the way life's molecules interact in ...

Biochemistry Sep 28, 2012

Bioengineers design rapid, easy-to-use diagnostic tests

(Phys.org)—By mimicking nature's own sensing mechanisms, bioengineers at UC Santa Barbara and University of Rome Tor Vergata have designed inexpensive medical diagnostic tests that take only a few minutes to perform. Their ...