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Bio & Medicine Jul 10, 2024

Nanoparticle-based delivery system could offer treatment for diabetics with rare insulin allergy

Up to 3% of people with diabetes have an allergic reaction to insulin. A team at Forschungszentrum Jülich has now studied a method that could be used to deliver the active substance into the body in a masked form—in the ...

Cell & Microbiology Jul 10, 2024

Unexpected phage protein function discovered in bacteria battle

An unexpected find has enabled important progress to be made in the battle against harmful bacteria. An international team of researchers, led by Professor Peter Fineran from the University of Otago, investigated a particular ...

Planetary Sciences Jul 10, 2024

Modeling study proposes a diamond layer at the core-mantle boundary on Mercury

A recent study in Nature Communications by scientists from China and Belgium suggests that Mercury's core-mantle boundary (CMB) includes a diamond layer, potentially up to 18 kilometers thick, deep within the planet's interior.

Bio & Medicine Jul 9, 2024

Team pioneers a 'one-pot platform' to promptly produce mRNA delivery particles

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network. The programmer, armed with the lifesaving ...

Cell & Microbiology Jul 5, 2024

Study finds ways to enhance transcription factor activity

Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to producing messenger RNAs from protein-coding genes. Denes Hnisz's lab, in collaboration with Martin Vingron's ...

Cell & Microbiology Jul 5, 2024

'Vaults' within germ cells offer more than safekeeping

Maternal messenger RNAs (mRNAs), located within the cytoplasm of an immature egg, are crucial for jump starting development. Following fertilization, these mRNAs are passed onto the zygote, the first newly formed cell.

Cell & Microbiology Jul 3, 2024

New mRNA technology turns cells into long-lasting drug factories

A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan ...

Cell & Microbiology Jul 2, 2024

UV radiation damage leads to ribosome roadblocks, causing early skin cell death

In a recent study, researchers at Johns Hopkins Medicine suggest that the cell's messenger RNA (mRNA)—the major translator and regulator of genetic material—along with a critical protein called ZAK—spurs the cell's ...

Molecular & Computational biology Jul 2, 2024

Research shows how RNA 'junk' controls our genes

Researchers at Arizona State University have made a significant advance in understanding how genes are controlled in living organisms. The new study, published in the journal Nucleic Acids Research, focuses on critical snippets ...

Cell & Microbiology Jul 1, 2024

Protein nanocages pave the way for effective mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host ...

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