Planarians offer a better view of eye development

Planarian flatworms have come under intense study for their renowned ability to regenerate any missing body part, even as adults. But now they may take on a starring role as a model system for studying eye development and ...

Structure of RNAi complex now crystal clear

Researchers at the Whitehead Institute and Memorial Sloan-Kettering Cancer Center have defined and analyzed the crystal structure of a yeast Argonaute protein bound to RNA. This complex plays a key role in the RNA interference ...

lobSTR algorithm rolls DNA fingerprinting into 21st century

As any crime show buff can tell you, DNA evidence identifies a victim's remains, fingers the guilty, and sets the innocent free. But in reality, the processing of forensic DNA evidence takes much longer than a 60-minute primetime ...

Planarian genes that control stem cell biology identified

Despite their unassuming appearance, the planarian flatworms in Whitehead Institute Member Peter Reddien's lab are revealing powerful new insights into the biology of stem cells—insights that may eventually help such ...

Noncoding RNAs alter yeast phenotypes in a site-specific manner

Personal change can redefine or even save your life—especially if you are one of a hundred yeast cell clones clinging to the skin of a grape that falls from a sun-drenched vine into a stagnant puddle below. By altering ...

Chaos in the cell's command center

A defective operating system is never a good thing. Like computers, our cells depend on operating systems to drive normal functions. Gene expression programs comprise the software code our cells rely on, with each cell type ...

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