Bringing bad proteins back into the fold

A study led by UT Southwestern has identified a mechanism that controls the activity of proteins known as chaperones, which guide proteins to fold into the right shapes. The findings, published online today in Nature Communications, ...

Giving cells an appetite for viruses

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve ...

Finding the Achilles' heel of a killer parasite

Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes—parasitic flatworms that cause the little-known tropical disease schistosomiasis. The findings, published ...

Escape artists: How vibrio bacteria break out of cells

As soon as the foodborne pathogen Vibrio parahaemolyticus infects a human intestinal cell, the bacteria are already planning their escape. After all, once it is in and multiplies, the bacterium must find a way out to infect ...

Understanding the circadian clocks of individual cells

Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means. These findings, published online May 1 in PNAS and May 27 in eLife, ...

Viewing dopamine receptors in their native habitat

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells. But despite their importance in physiology ...

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