Targeting Nsp1 protein could be a pathway for COVID-19 therapy
A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes that promote viral replication provides hope for new COVID-19 treatments.
A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes that promote viral replication provides hope for new COVID-19 treatments.
Molecular & Computational biology
Feb 16, 2021
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28
A study led by UT Southwestern has identified a mechanism that controls the activity of proteins known as chaperones, which guide proteins to fold into the right shapes. The findings, published online today in Nature Communications, ...
Molecular & Computational biology
Feb 11, 2021
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174
A set of biomarkers not traditionally associated with cell fate can accurately predict how genetically identical cells behave differently under stress, according to a UT Southwestern study. The findings, published by Cell ...
Cell & Microbiology
Jan 11, 2021
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28
A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve ...
Cell & Microbiology
Dec 16, 2020
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98
A team led by UT Southwestern has derived a new "intermediate" embryonic stem cell type from multiple species that can contribute to chimeras and create precursors to sperm and eggs in a culture dish.
Cell & Microbiology
Dec 3, 2020
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218
UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.
Biotechnology
Nov 12, 2020
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234
Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes—parasitic flatworms that cause the little-known tropical disease schistosomiasis. The findings, published ...
Cell & Microbiology
Sep 24, 2020
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147
As soon as the foodborne pathogen Vibrio parahaemolyticus infects a human intestinal cell, the bacteria are already planning their escape. After all, once it is in and multiplies, the bacterium must find a way out to infect ...
Cell & Microbiology
Aug 18, 2020
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58
Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means. These findings, published online May 1 in PNAS and May 27 in eLife, ...
Cell & Microbiology
Jul 2, 2020
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54
Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells. But despite their importance in physiology ...
Biochemistry
Jun 11, 2020
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37