The cytoskeleton is a structure that not only helps cells maintain their shape and internal organisation, but also enables them to perform functions like movement and migration to sites far from the place where they originated. ...
Cell & Microbiology
Mar 12, 2019
0
47
In recent years, it has become evident that the spatial organisation of the genome is key for its function. This depends on a number of factors, including the cohesin protein complex. This essential complex is present in ...
Cell & Microbiology
Jun 5, 2018
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62
Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre (CNIO) have discovered how certain proteins ensure the repair of errors introduced ...
Molecular & Computational biology
Apr 6, 2021
0
261
Ana Losada, from the Spanish National Cancer Research Centre (CNIO), is the scientist who identified cohesin in vertebrates, a protein that is essential in cell division. Losada has studied cohesin since she identified it ...
Cell & Microbiology
Aug 11, 2020
0
7
Since the emergence of molecular genetics more than 50 years ago, scientists have tried to isolate haploid mammalian cells, that is, cells with half the number of chromosomes contained in somatic cells. Haploid cells are ...
Cell & Microbiology
Jul 17, 2019
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16
A defense mechanism that human cells possess against viruses such as monkeypox, herpes simplex and human papillomavirus—all double-stranded DNA viruses—relies on proteins that patrol the cell, acting as sensors of the ...
Biotechnology
Nov 29, 2022
0
39
The principle that form follows function does not only apply to design and architecture. It also applies to biology. Every organism is a universe that lives thanks to the activities of tens of thousands of nanomachines, whose ...
Molecular & Computational biology
Jul 7, 2021
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10
Getting energy and nutrients from the environment—eating—is such an important function that it has been regulated through sophisticated mechanisms over hundreds of millions of years. Some of these mechanisms are only ...
Molecular & Computational biology
Jun 16, 2021
0
12
The (when stretched) two-meter-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information. When genes must be accessed for transcription, the DNA double ...
Molecular & Computational biology
Apr 13, 2021
0
18
A research team led by Daniel Lietha has just published in The EMBO Journal the mechanistic details of the activation of the focal adhesion kinase (FAK) on lipid membranes. Lietha started this research during his work at ...
Cell & Microbiology
Aug 11, 2020
0
4
