Protein 'comet tails' propel cell recycling process

Several well-known neurodegenerative diseases, such as Lou Gehrig's (ALS), Parkinson's, Alzheimer's, and Huntington's disease, all result in part from a defect in autophagy - one way a cell removes and recycles misfolded ...

Gorilla origins of the last two AIDS virus lineages confirmed

Two of the four known groups of human AIDS viruses (HIV-1 groups O and P) have originated in western lowland gorillas, according to an international team of scientists from the Perelman School of Medicine at the University ...

Study uncovers secrets of a clump-dissolving protein

Workhorse molecules called heat-shock proteins contribute to refolding proteins that were once misfolded and clumped, causing such disorders as Parkinson's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. ...

New technology directly reprograms skin fibroblasts for a new role

As the main component of connective tissue in the body, fibroblasts are the most common type of cell. Taking advantage of that ready availability, scientists from the Perelman School of Medicine at the University of Pennsylvania, ...

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