The National Institutes of Health (NIH) is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation. It comprises 27 separate institutes, centers, and offices which includes the Office of the Director. Francis S. Collins is the current Director. As of 2003, the NIH was responsible for 28%—about US$26.4 billion—of the total biomedical research funding spent annually in the U.S., with most of the rest coming from industry. The NIH's research is divided into two parts: the NIH Extramural Research Program is responsible for the funding of biomedical research outside the NIH, while the NIH Intramural Research Program (IRP) is the internal research program of the NIH, known for its synergistic approach to biomedical science. With 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, the IRP is the largest biomedical research institution on earth.


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Research team first to develop 3D structure of twinkle protein

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...

Fluorescent dot synthesis gets an eco-friendly 'glow up'

Fluorescent "dots"—that is, tiny particles that can emit light—have a multitude of promising biomedical applications, from helping clinicians to better identify tumor margins to delivering a drug deep in the body. However, ...

Scientists may need to rethink which genes control aging

To better understand the role of bacteria in health and disease, National Institutes of Health researchers fed fruit flies antibiotics and monitored the lifetime activity of hundreds of genes that scientists have traditionally ...

Turning off 'junk DNA' may free stem cells to become neurons

For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, NIH researchers report for the first time that ancient viral genes ...

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