Mayo Clinic researchers have developed an animal model that can test the function of two prominent tumor suppressor genes, p16 and p19, in the aging process. Scientists knew that both these genes were expressed at increased ...
May 30, 2008
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Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research. The findings suggest phage therapy could provide a potential treatment ...
Cell & Microbiology
Jul 24, 2020
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Social distancing guidelines have reduced the spread of COVID-19, but lockdowns and isolation also have created or aggravated other well-being concerns, reports new research. Mayo Clinic investigators found a significant ...
Social Sciences
Mar 4, 2021
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Mayo Clinic researchers have gained insights into the function of a member of a family of specialized proteins called histone chaperones. Using nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography, they ...
Biochemistry
Mar 1, 2012
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Cells in the human body, the building blocks of life, are arranged in a precise way. That's necessary because pathways and spaces provide a means for cells to communicate, collaborate and function within the specific tissue ...
Cell & Microbiology
Jun 26, 2023
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Mayo Clinic researchers have shown that a molecule called Cul4 helps to deposit DNA-packaging histone proteins onto DNA, an integral step in cramming yards of genetic code into compact coils that can fit into each cell. When ...
Cell & Microbiology
Nov 7, 2013
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With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules. When a person is young, the immune system responds and eliminates senescent cells, ...
Cell & Microbiology
Dec 4, 2023
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A Mayo Clinic researcher and his collaborators have developed an online analytic tool that will speed up and enhance the process of re-engineering cells for biomedical investigation. CellNet is a free-use Internet platform ...
Cell & Microbiology
Aug 28, 2014
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Pten (short for phosphatase and tensin homolog) is a tumor suppressor that is defective in about 20-25 percent of all patients with cancers. Mayo Clinic researchers now have discovered that Pten safeguards against tumor formation ...
Cell & Microbiology
Jun 2, 2016
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