Even in this "age of the genome," much about genes remains shrouded in mystery. This is especially true for "cryptic mutations"—mutated genes that are hidden, and have unexpected effects on traits that are only revealed ...
Biotechnology
May 6, 2019
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208
Every cell in our body has exactly the same DNA, yet every cell is different. A cell's identity is determined by the subset of genes that it activates. But how does a cell know which genes to turn off and which to turn on? ...
Biotechnology
Mar 13, 2014
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1
Who's about to become the biggest beast in the Big Data forest? A group of math and computing experts have arrived at what they say is a clear answer. It's not You Tube or Twitter, two social media sites that gobble up awesome ...
Biotechnology
Jul 7, 2015
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100
At the same time that a cell's DNA gets duplicated, a third of it gets super-compacted into repetitive clumps called heterochromatin. This dense packing serves to repress or "silence" the DNA sequences within -- which could ...
Cell & Microbiology
Oct 16, 2011
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0
Men and women differ in plenty of obvious ways, and scientists have long known that genetic differences buried deep within our DNA underlie these distinctions. In the past, most research has focused on understanding how the ...
Biotechnology
Aug 18, 2014
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In 2003, the Human Genome Project revealed to the world the three billion chemical units within human DNA. Since that time, scientists have designed many ways to organize and assess this overwhelmingly large amount of information. ...
Evolution
Dec 18, 2018
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180
The nucleus of a cell, which houses the cell's DNA, is also home to many structures that are not bound by a membrane but nevertheless exist as distinct compartments. A team of Cold Spring Harbor Laboratory (CSHL) scientists ...
Cell & Microbiology
Dec 19, 2010
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0
Scientists at Cold Spring Harbor Laboratory (CSHL) have harnessed the still untapped power of genome editing to improve agricultural crops. Using tomato as an example, they have mobilized CRISPR/Cas9 technology to rapidly ...
Biotechnology
Sep 14, 2017
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151
A cell's genome maintains its integrity by organizing some of its regions into a super-compressed form of DNA called heterochromatin. In the comparatively simple organism fission yeast, a cellular phenomenon known as RNA ...
Cell & Microbiology
Nov 13, 2011
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0
The timing of flowering in plants is critical. It can have profound effects on flower, fruit, and seed production, and consequently agricultural yields. This process is known to depend on daylight and temperature cues. However, ...
Biotechnology
Nov 11, 2012
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