Stem cells know how to open up and unwind

Research led by the Babraham Institute with collaborators in the UK, Canada and Japan has revealed a new understanding of how an open genome structure supports the long-term and unrestricted developmental potential in embryonic ...

Packaging and unpacking of the genome

DNA represents a dynamic form of information, balancing efficient storage and access requirements. Packaging approximately 1.8m of DNA into something as small as a cell nucleus is no mean feat, but unpacking it again to access ...

Aging can be good for you (if you're a yeast)

It's a cheering thought for anyone heading towards their golden years. Research from the Babraham Institute has shown that ageing can be beneficial - albeit so far only in yeast.

Yeast cells optimize their genomes in response to the environment

Researchers at the Babraham Institute and Cambridge Systems Biology Centre, University of Cambridge have shown that yeast can modify their genomes to take advantage of an excess of calories in the environment and attain optimal ...

What can worms tell us about human aging?

What can worms tell us about human ageing? A lot more than you'd think; as research led by the Babraham Institute but involving researchers from multiple disciplines drawn together from across the world has shown. In a cluster ...

RNA binding proteins help T cells pick their weapons before battle

Scientists at the Babraham Institute have shown that two RNA binding proteins hold the key to a stronger immune response to influenza in mice. Their findings, published today in Nature Communications, reveal that the absence ...

Controlling gene activity in human development

Researchers at the Babraham Institute have revealed a new understanding of the molecular switches that control gene activity in human embryonic stem cells. This insight provides new avenues for improving the efficiency of ...

Preventing a genetic uprising in early life

Molecules called endosiRNAs help us avoid genetic chaos, according to a new study from a team at the Babraham Institute. Much of the human genome contains pieces of DNA called transposons, a form of genetic parasite. When ...

A brain switch that helps worms keep their cool

How our bodies sense and respond to environmental changes are fundamental biological questions. In particular, understanding how organisms sense and cope with warming temperatures is key for the survival of species and it ...

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