The BBSRC-supported Babraham Institute undertakes international quality life sciences research to generate new knowledge of biological mechanisms underpinning ageing, development and the maintenance of health. The Institute’s research provides greater understanding of the biological events that underlie the normal functions of cells and the implication of failure or abnormalities in these processes. Research focuses on signalling and genome regulation, particularly the interplay between the two and how epigenetic signals can influence important physiological adaptations during the lifespan of an organism. By determining how the body reacts to dietary and environmental stimuli and manages microbial and viral interactions, we aim to improve wellbeing and healthier ageing.

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Vitamins A and C help erase cell memory

Vitamins A and C aren't just good for your health, they affect your DNA too. Researchers at the Babraham Institute and their international collaborators have discovered how vitamins A and C act to modify the epigenetic 'memory' ...

Mouse epigenetic aging clock uncovered

Ageing in humans (and animals) can be seen as either an inevitable process of wear and tear or as an inherent biological programme by which the lifespan of each species is more or less predetermined. Recent research has shown ...

Old skin cells reprogrammed to regain youthful function

Research from the Babraham Institute has developed a method to "time jump" human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function. Work by researchers in the Institute's ...

How good bacteria control your genes

Scientists from the Babraham Institute near Cambridge in collaboration with colleagues from Brazil and Italy have discovered a way that good bacteria in the gut can control genes in our cells. The work, published today (9th ...

Stem cell secrets allow researchers to revamp reprogramming

Researchers from the Babraham Institute's Epigenetics research program have been able to learn more about naïve stem cell reprogramming following a genome wide functional screen. Their research, published today in Science ...

Understanding X-chromosome silencing in humans

Researchers have discovered new insights into how one of the two X-chromosomes is silenced during the development of female human embryos and also in lab-grown stem cells. X-chromosome silencing is essential for proper development ...

Detailed study reveals genes are constantly rearranged by cells

Moving genes about could help cells to respond to change according to scientists at the Babraham Institute in Cambridge, UK and the Weizmann Institute, Israel. Changing the location of a gene within a cell alters its activity. ...

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