Molecular & Computational biology

One DNA letter can trigger complete sex reversal

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice. In the new study, published in Nature Communications, a single-letter insertion in a non-coding ...

Astronomy

What if dark matter came in two states?

The absence of a signal could itself be a signal. This is the idea behind a new study published in the Journal of Cosmology and Astroparticle Physics, which aims to redefine how we search for dark matter, showing that it ...

Physicists zero in on the mass of the fundamental W boson particle

When fundamental particles are heavier or lighter than expected, physicists' understanding of the universe can tip into the unknown. A particle that is just beyond its predicted mass can unravel scientists' assumptions about ...

AI uncovers hidden immune defenses inside bacteria

Researchers at the Massachusetts Institute of Technology (MIT) have discovered thousands of new proteins that protect bacteria from virus attacks using an AI system called DefensePredictor. What would usually take months ...

A 'stemness checkpoint' helps control stem cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages. For nearly two decades, ...

Why anti-cancer drugs do not always live up to expectations

For more than a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations. The biology looked promising. Many cancers depend on oncogenes that "Bromo- and Extra-Terminal domain" ...

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Uncharted island will soon appear on nautical charts

A 93-strong international expedition team has been exploring the northwestern Weddell Sea in the Antarctic on board the Alfred Wegener Institute's icebreaker Polarstern since February 8, 2026. In this key region for global ...

DNA evidence reveals a Stone Age population collapse in France

By analyzing DNA of ancient skeletons at a Neolithic burial site near Paris, an international team of researchers has uncovered evidence of a dramatic population replacement 5,000 years ago. The findings indicate that the ...

Mathematical model predicts fish freshness in real time

Every day, fish caught in oceans and seas around the world pass through a long journey before reaching supermarkets, restaurants, and home kitchens. Along the way, their freshness steadily declines, often in ways that are ...

March smashes heat records for continental US

March's persistent unseasonable heat was so intense that the continental United States registered its most abnormally hot month in 132 years of records, according to federal weather data. And the next year or so looks to ...

Soaring petrol prices are hurting more than your wallet

Australians don't need an economist to tell them they're hurting at the petrol pump. They feel it every time they pull into a service station, every time they rethink a planned holiday, or every time they've had to squeeze ...

How noise limits today's quantum circuits

Imagine you're trying to build a very long, complicated chain of dominoes. The aim is that each domino hits the next one perfectly, all the way down the line, producing an amazing result at the end. A quantum circuit is like ...

How electric vehicles could back up the power system

Electric vehicles (EVs) could do more for our environment than simply replace gasoline. Published in Joule, a new assessment of EV charging strategies suggests that EVs could serve as a vast network of mobile batteries, storing ...

Rudeness may be rewarded—as a response to rudeness

If you don't have anything nice to say, perhaps it's OK to say it anyway—if responding to someone who has treated you or your team rudely, new Cornell research suggests. Civil responses to disrespectful behavior remain the ...

How disinfectants influence microbes across hospital rooms

Just because a topical antiseptic is swabbed on the skin doesn't mean it stays on the skin. In a new study, Northwestern University scientists studied how a powerful antiseptic, called chlorhexidine, affects bacteria in hospital ...

Tracking Arctic freshwater flow from space

Arctic rivers wind through remote tundra and boreal forests, freezing solid in winter and surging each spring with snowmelt, eventually emptying into the ocean. Runoff—water that does not soak into the ground but instead ...

Online ad fraud is a feature, not a bug

Technological advancements and the dynamics of the platform economy make rooting out fraud more complicated than it may seem. With print media circulation and broadcast television viewership in free fall, a lot is riding ...

Saturn-mass world discovered orbiting two low-mass stars

Researchers report the discovery of a Saturn-sized exoplanet orbiting two M-dwarf stars, which are smaller and cooler than our sun. The findings from this discovery were published in the The Astronomical Journal and were ...

Planet trapped record heat in 2025: UN

The amount of heat trapped by Earth reached record levels in 2025, with the consequences of such warming feared to last for thousands of years, the UN warned Monday.

Measuring irreversibility in gene transcription

Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, irreversible processes, such as transcribing DNA into RNA, to keep life going. But how that irreversibility ...