A new laser source for infrared chemical imaging: a promising tool for early cancer diagnostic

March 23, 2018, Université de Limoges
Credit: Université de Limoges

Sébastien Février, researcher at XLIM (CNRS/Université de Limoges), and his team demonstrated that a bench-top, optical fibre-based laser source can be used to perform infrared spectromicroscopy with a precision rivaling, and in some regards even surpassing, that of experiments at large-scale synchrotron facilities.

Synchrotrons are accelerator facilities that provide powerful infrared light used for analyzing the chemical content of biological tissues with micrometer scale resolution. This high precision chemical imaging technique enables an early diagnosis of pathologies such as cirrhosis and cancer. However, up to now, the very high cost of ownership and limited availability of has hindered the deployment of chemical imaging technique in the hospital.

Replacing the with a compact laser source could unleash the potential of this and ease its implementation in the hospital, thus accelerating access to diagnosis and treatment.

The results were published in Optica, an international peer-reviewed journal dedicated to cutting-edge research in photonics.

The demonstration involved a consortium including researchers from XLIM and the synchrotron Soleil in Saclay as well as engineers from the company Novae, a start-up founded in 2013 by researchers from the University of Limoges. Novae targets industrial and scientific markets such as laser-based bio-imaging and materials micro-processing. The is now part of Novae's portfolio of products.

Explore further: New infrared imaging technique reveals molecular orientation of proteins in silk fibres

More information: Manli Wang et al. Synchrotron radiation-based Fourier-transform infrared spectromicroscopy for characterization of the protein/peptide distribution in single microspheres, Acta Pharmaceutica Sinica B (2015). DOI: 10.1016/j.apsb.2015.03.008

Related Stories

A new dimension in chemical nanoimaging

February 23, 2017

Researchers report the development of hyperspectral infrared nanoimaging based on Fourier transform infrared nanospectroscopy (nano-FTIR), enabling highly sensitive spectroscopic imaging of chemical compositions with nanoscale ...

Recommended for you

Neutron stars may hold an answer to neutron puzzle on Earth

August 15, 2018

According to University of Illinois physicist Douglas H. Beck, "Neutrons play some unusual roles in our world. Free neutrons decay in about 900 s but, bound in nuclei, they are stable and make up somewhat more than half the ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.