Leading stem cell scientist cleared of misconduct charges

August 28, 2015 byMaria Cheng
Leading stem cell scientist cleared of misconduct charges
In this Friday, July 30, 2010 file photo, Dr. Paolo Macchiarini looks on during a press conference where he announced that his surgical team successfully transplanted the windpipes of two cancer patients with an innovative procedure that uses stem cells to allow a donated trachea to regenerate tissue and create an organ that is biologically close to the original, Florence, Italy. Sweden's Karolinska Institute said on Friday, Aug. 28, 2015 that Macchiarini, a leading stem cell scientist accused of unethical behavior, has been cleared of scientific misconduct though he sometimes acted without due care. (AP Photo/Lorenzo Galassi, File)

Sweden's Karolinska Institute says a leading stem cell scientist accused of unethical behavior has been cleared of scientific misconduct though he sometimes acted without due care.

In a statement released on Friday, the university said complaints leveled against Dr. Paolo Macchiarini—who has created wind pipes using patients' stem cells—did not qualify as scientific misconduct, overturning a previous investigation in May which found him guilty.

After examining further documents submitted by Macchiarini, Karolinska's vice-chancellor Anders Hamsten concluded there were flaws in Macchiarini's work "but nothing that can be considered scientific misconduct." The previous investigation had claimed, among other things, that Macchiarini "selectively described" certain minor problems in patients while omitting serious complications.

"To have been falsely accused of serious misconduct is every researcher's nightmare," Macchiarini said in an email. He said the accusations were extremely damaging to him and the field of regenerative medicine; the Swedish Research Council froze his grants in June.

Macchiarini has been instructed to submit corrected information to the journals that published some of his work to clarify the mistakes identified by the university's inquiry.

Macchiarini said he would speak with Karolinska about immediately ensuring the reinstatement of his research grants. He and colleagues have developed a novel technique of seeding either donated or synthetic wind pipes with stem cells of patients to prevent rejection and are now expanding their work to include other organs.

"I feel it is extremely important that public confidence is restored in this field now," he said. "It is only through the trust of present patients willing to take part in experimental surgeries that patients of the future will have a chance to benefit."

Explore further: Sweden hospital in lab-made windpipe transplant

Related Stories

Sweden hospital in lab-made windpipe transplant

July 7, 2011

A 36-year-old man who had tracheal cancer has received a new lab-made windpipe seeded with his own stem cells in a procedure in Sweden they call the first successful attempt of its kind, officials said Thursday.

Feds: Ex-Harvard prof faked data in experiments

September 5, 2012

(AP)—Federal investigators have found that a Harvard University psychology professor who resigned after being accused of scientific misconduct fabricated data and manipulated results in experiments.

Researchers transplant regenerated oesophagus

April 15, 2014

Tissue engineering has been used to construct natural oesophagi, which in combination with bone marrow stem cells have been safely and effectively transplanted in rats. The study, published in Nature Communications, shows ...

Recommended for you

Research helps students excel on science exams

January 15, 2019

A new study released today reveals that helping lower-income high school freshman to regulate their test-taking anxiety can cut their biology course failure rates in half. The study, published in Proceedings of the National ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.