Low-calorie diet: Longer life?

April 5, 2006

St. Louis scientists are starting a 2-year study to confirm a short Louisiana State University trial suggesting low-calorie diets result in longer life.

Scientists at the St. Louis-based Washington University School of Medicine more than a decade ago demonstrated caloric restriction increased the lifespan in mice and rats by about 30 percent by changing some of the markers associated with aging, such as DNA damage.

Now Dr. John Holloszy, a Washington University professor of medicine, and Dr. Luigi Fontana, an assistant professor of medicine, are launching the study.

"We know people on calorie restriction will lose weight," said Fontana. "But this study isn't a weight-loss study. We're hoping to learn more about whether calorie restriction can alter the aging process."

Holloszy added, "If we can demonstrate (calorie restriction) changes these markers of aging ... we'll have a pretty good idea that it's somehow influencing the aging process at the cellular level."

Copyright 2006 by United Press International

Explore further: Designing local well-being indicators—the case of the Grenoble metropolitan area

Related Stories

What can Facebook learn about you from just one click?

November 15, 2017

How effective is psychological targeting in advertising? Dr Sandra Matz, a former PhD student at Cambridge now based at Columbia University, and her co-authors, including Dr David Stillwell from the Cambridge Psychometrics ...

Recommended for you

Heavy nitrogen molecules reveal planetary-scale tug-of-war

November 17, 2017

Nature whispers its stories in a faint molecular language, and Rice University scientist Laurence Yeung and colleagues can finally tell one of those stories this week, thanks to a one-of-a-kind instrument that allowed them ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.