More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't ...
Analytical Chemistry
Aug 3, 2016
0
7
Drugs to treat cancer and Alzheimer's disease usually target the active sites of specific protein molecules sustaining the disease. Traditional drug design views proteins as rigid 3-D objects with active sites consisting ...
Biochemistry
Jun 6, 2016
0
107
Researchers at Aarhus University have described one of the cell's key enzymes, the calcium pump, in its decisive moment—a so-called transition state. These findings provide a very detailed picture of how one of the most ...
Biochemistry
May 9, 2016
0
6
EPFL scientists have elucidated for the first time how a notoriously elusive serotonin receptor functions with atom-level detail. The receptor transmits electrical signals in neurons and is involved in various disorders, ...
Biochemistry
Apr 21, 2016
0
42
Protein kinases, most scientists would agree, regulate nearly every aspect of cell life. It is no surprise, then, that having faulty protein kinases may lead to a number of human conditions, including cardiovascular diseases, ...
Biochemistry
Apr 8, 2016
0
298
Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good—modifying the viruses to carry drug molecules, for example.
Cell & Microbiology
Mar 29, 2016
0
29
Infinitesimal fluctuations occurring on the milli- and even nano-second time scales within the three-dimensional structure of enzymes may be one of the keys to explaining protein function. Professor Nicolas Doucet's team ...
Biochemistry
Dec 10, 2015
0
8
New research by a Florida State University chemistry professor uses some of the world's most powerful magnets to put a bullseye on the flu virus.
Biochemistry
Nov 2, 2015
0
14
Searching for the precise, complexly folded three-dimensional structure of a protein can be like hacking through a jungle without a map: a long, intensive process with uncertain direction. University of Illinois researchers ...
Biochemistry
Oct 15, 2015
0
536
Scientists from New Zealand and Australia have created the first three-dimensional image of a key protein involved in the development of blood and other cancers.
Biochemistry
Oct 8, 2015
0
12
