Neutron study of glaucoma drugs offers clues about enzyme targets for aggressive cancers
New insights from neutron analysis of glaucoma drugs and their enzyme target may help scientists design drugs that more effectively target aggressive cancers.
New insights from neutron analysis of glaucoma drugs and their enzyme target may help scientists design drugs that more effectively target aggressive cancers.
Biochemistry
Feb 12, 2018
0
34
Researchers have new insights into how protective antibodies attack dengue viruses, which could lead to more effective dengue fever vaccines and drug therapies.
Cell & Microbiology
Dec 19, 2017
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32
Yaser Hashem's team at the Laboratoire Architecture et Réactivité de l'ARN at CNRS's has discovered a new potential therapeutic target - located in the ribosome - to combat trypanosomes parasites. Using cryo-electron microscopy, ...
Cell & Microbiology
Oct 26, 2017
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2
Picture a brand-new, unsharpened pencil. The graphite at its core can't be used for writing until a pencil sharpener chews away its wooden tip.
Cell & Microbiology
Oct 24, 2017
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4
A yeast protein that evolved from scratch can fold into a three-dimensional shape—contrary to the general understanding of young proteins—according to new research led by the University of Arizona.
Biochemistry
Oct 20, 2017
1
190
A University of Alabama at Birmingham team led by Jamil Saad, Ph.D., has solved the last unknown protein structure of HIV-1, the retrovirus that can cause AIDS.
Biochemistry
Oct 19, 2017
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52
With the heightened concerns over the dangerous side effects of the once-popular antidiabetic drug Avandia, researchers at The Scripps Research Institute (TSRI) in Jupiter, Florida, are working to understand how small molecules, ...
Biochemistry
Sep 30, 2017
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93
Antibodies are a powerful weapon system in defending our body against invaders such as bacteria and viruses. Each antibody consists of four amino acidpolypeptide chains: two heavy chains and two light chains joined to form ...
Biochemistry
Sep 20, 2017
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2
The lack of vitamin A in food is a major cause of health problems worldwide and can lead to blindness and even death. This is especially a problem in threshold or third-world countries, where children are likely to suffer ...
Biotechnology
Jul 21, 2017
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11
When you lift weights, carry heavy boxes, or engage in physical activity, the cells in your body stretch and deform to accommodate your movements. But how do your cells recover, or return to their original state, once you ...
Biotechnology
Jun 20, 2017
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22