Flipping the 'off' switch on cell growth

A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery ...

How infectious bacteria hibernate through treatment

Disease-causing bacteria can develop resistance to antibiotics which are then no longer effective in treating infection, yet they also have another tactic to avoid being killed off by antibiotic treatment. Some cells of the ...

Surface protein editing in bacteria

University of Minnesota researchers have discovered this previously unknown signaling pathway that regulates surface proteins on bacteria that can lead to new targets for antibiotics.

Control of a mitochondrial protective mechanism identified

Mitochondria are essential for normal functioning of almost all cells, since they are the main production sites of the energy-carrying molecule adenosine triphosphate (ATP). In addition, mitochondria are the key sites of ...

Infertility's roots in DNA packaging

Pathological infertility is a condition affecting roughly 7 percent of human males, and among those afflicted, 10 to 15 percent are thought to have a genetic cause. However, pinpointing the precise genes responsible for the ...

New possible target for treating major common diseases

There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a family of receptors known as Frizzleds, researchers at Karolinska Institutet in Sweden believe. ...

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