PLoS Computational Biology is a peer-reviewed computational biology journal established in 2005 and published by the nonprofit Public Library of Science in association with the International Society for Computational Biology. Its Editor in Chief is Philip Bourne. All articles are open access and licensed under the Creative Commons Attribution License. The journal is well-known beyond its core field for its Ten Simple Rules series of articles that capture the essence of selected aspects of research in computational biology or in science more generally, e.g. how to present a poster, how to collaborate, or how to edit Wikipedia. Due to their free licensing, files from PLoS Computational Biology can be reused in places other than the journal s website, e.g. to illustrate Wikipedia articles.
Scientists create first viable mathematical model of a key anti-Salmonella defense system
Scientists have created the first validated mathematical model of an important cellular defense mechanism against the bacterium Salmonella, according to a new study in PLOS Computational Biology.
Mouth clicks used in human echolocation captured in unprecedented detail
Like some bats and marine mammals, people can develop expert echolocation skills, in which they produce a clicking sound with their mouths and listen to the reflected sound waves to "see" their surroundings. A new study published ...
Insect vector feeding recognized by machine learning
Scientists have used machine learning algorithms to teach computers to recognize the insect feeding patterns involved in pathogen transmission. The study, published in PLOS Computational Biology, also uncovers plant traits ...
Geometry, programmed death might have enabled evolution of multicellularity
Geometry and programmed cell death may have helped along the evolution of multicellular life, according to new research led by SFI Omidyar Fellow Eric Libby.
New insights into the evolution of cooperation in spatially structured populations
Researchers have analyzed a new mathematical model to investigate how a population's spatial structure affects the evolution of cooperation. Jorge Peña of the Max Planck Institute for Evolutionary Biology in Plön, Germany, ...
New algorithm tracks neurons in bendy brain of freely crawling worm
Scientists at Princeton University have developed a new algorithm to track neurons in the brain of the worm Caenorhabditis elegans while it crawls. The algorithm, presented in PLOS Computational Biology by Jeffrey Nguyen ...
The billion dollar game of strategy: The effect of farmers' decisions on pest control
Researchers say that the actions of individual farmers should be considered when studying and modelling strategies of pest control.
Team develops groundbreaking membrane analysis tool
To understand the complexity of cell membranes, scientists count on a panoply of technological tools that allow them to analyze microscopic images. A multidisciplinary team from VIB-KU Leuven has just added an important one ...
Spread of diseases in farmed animals shown using social network analysis
Researchers have shown that looking at movements of operators and vehicles between farms in the same way we look at contacts in social networks can help explain the spread of dangerous infectious diseases of livestock, such ...
Why some humans developed a taste for milk and some didn't
Imagine a dinner party somewhere in Italy to which, as it turns out, my dad has been invited. On the menu tonight is a sliced tomato, basil and mozzarella salad, pasta with a creamy mushroom sauce topped with parmesan cheese, ...