New-found molecular signature keeps key genes ready for action

During development, scores of molecular signals prod cells to take on specialized identities and functions. In response to some of these signals, the cellular machinery awakens specific genes called 'immediate early genes' ...

Explainable AI for decoding genome biology

Researchers at the Stowers Institute for Medical Research, in collaboration with colleagues at Stanford University and Technical University of Munich have developed advanced explainable artificial intelligence (AI) in a technical ...

Chromatin remodelers never rest to keep our genome open

Chromatin remodelers are needed to take nucleosomes away from DNA in order to make room for transcription factors to bind, and regulate the activity of our genes. It has been unclear how dynamic this process is. Researchers ...

Silk Road contains genomic resources for improving apples

The fabled Silk Road—the 4,000-mile stretch between China and Western Europe where trade flourished from the second century B.C. to the 14th century A.D. - is responsible for one of our favorite and most valuable fruits: ...

European and American maize: Same same, but different

German researchers decoded the European maize genome. In comparison to North American maize lines, they discovered variations that underlie phenotypic differences and may also contribute to the heterosis effect. A better ...

RNA key in helping stem cells know what to become

Look deep inside our cells, and you'll find that each has an identical genome -a complete set of genes that provides the instructions for our cells' form and function.

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