How a shape-shifting DNA-repair machine fights cancer

(Phys.org) —Maybe you've seen the movies or played with toy Transformers, those shape-shifting machines that morph in response to whatever challenge they face. It turns out that DNA-repair machines in your cells use a similar ...

Quality control of mitochondria as a defense against disease

Scientists from the Montreal Neurological Institute and Hospital in Canada have discovered that two genes linked to hereditary Parkinson's disease are involved in the early-stage quality control of mitochondria. The protective ...

Signalling pathway links local and systemic plant immunity

(Phys.org) —When plants discover a pathogen, they prepare for system-wide attack so they are ready to fight on all levels. Working with colleagues, Annegret Ross and Yusuke Saijo of the Max Planck Institute for Plant Breeding ...

Study reveals how to better master stem cells' fate

(Phys.org) —USC scientist Qi-Long Ying and a team of researchers have long been searching for biotech's version of the fountain of youth—ways to encourage embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs) to ...

CNIO researchers delve into the behavior of cohesins

Cohesins are protein complexes that join the two copies of each chromosome—called sister chromatids—to ensure that they are shared fairly between the daughter cells during cell division. In this way, each daughter cell ...

The benefits of bacteria for gut health

Scientists from the Emory University School of Medicine in Atlanta, United States have shown that specific gut bacteria are beneficial for maintaining a healthy intestine in the fruit fly Drosophila and mice and also contribute ...

A protein that can mean life or death for cells

Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum (ER), which is able to sense cellular stress and trigger either rescue responses ...

From blank round to a potently active substance?

A long-forgotten candidate for antiviral therapy is undergoing a renaissance: Since the 1970s, the small molecule CMA has been considered a potent agent against viral infections, yet it was never approved for clinical use. ...

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