Directly reprogramming a cell's identity with gene editing
Researchers have used CRISPR—a revolutionary new genetic engineering technique—to convert cells isolated from mouse connective tissue directly into neuronal cells.
Researchers have used CRISPR—a revolutionary new genetic engineering technique—to convert cells isolated from mouse connective tissue directly into neuronal cells.
Biotechnology
Aug 11, 2016
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194
The effectiveness of reprogramming cells into blood cells is thought to depend on the original cell type and reprogramming method. Researchers at CiRA show this assumption is actually the result of epigenetic effects, suggesting ...
Cell & Microbiology
Jul 28, 2016
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2
Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. These cells continually produce new ones, which appear on the skin surface after a few days. A study led by ICREA ...
Cell & Microbiology
Jul 28, 2016
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20
Whitehead Institute scientists have created a checklist that defines the "naive" state of cultured human embryonic stem cells (ESCs). Such cells can mature into almost any cell type and more closely resemble the unique molecular ...
Cell & Microbiology
Jul 14, 2016
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30
The United States is on course to experience a steep drop in the number of stem cell researchers in coming years as a large portion of academic scientists reach retirement age and younger scientists continue to leave academia ...
Cell & Microbiology
Jul 7, 2016
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9
A new procedure developed at Massachusetts General Hospital (MGH) may revolutionize the culturing of adult stem cells. In their report that has been published online prior to its appearance in the August 6 issue of Cell Stem ...
Cell & Microbiology
Jun 16, 2016
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13
Induced pluripotent stem cells hold promise for regenerative medicine because they can, in theory, turn into any type of tissue and because they are made from a patient's own adult cells, guaranteeing compatibility. However, ...
Cell & Microbiology
May 10, 2016
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67
If you want to harness the full power of stem cells, all you might need is an eraser.
Cell & Microbiology
Mar 17, 2016
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247
Combining the two most powerful biological tools of the 21st century, scientists at the Gladstone Institutes have modified how the genome of induced pluripotent stem cells (iPSCs) is read for the first time using a variation ...
Biotechnology
Mar 10, 2016
4
207
Scientists in China have finally succeeded in creating functioning sperm from mice in the laboratory. To accomplish this feat, the researchers coaxed mouse embryonic stem cells to turn into functional sperm-like cells, which ...
Cell & Microbiology
Feb 25, 2016
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752