Sample preparation is a fundamental laboratory technique encompassing all procedures required to convert a raw specimen into a form suitable for analytical measurement or experimental manipulation, while preserving analyte integrity and representativeness. It typically includes sampling, homogenization, separation, purification, concentration, and, when necessary, chemical derivatization. Methods vary by matrix and analytical modality (e.g., filtration, centrifugation, extraction, digestion, or fixation for microscopy), and are optimized to minimize contamination, losses, matrix effects, and chemical transformations. Rigorous sample preparation is critical for achieving accuracy, precision, sensitivity, and reproducibility in techniques such as chromatography, mass spectrometry, spectroscopy, and molecular biology assays.
New research led by University of Massachusetts Amherst assistant professor Jinglei Ping has overcome a major challenge to isolating and detecting molecules at the same time and at the same location in a microdevice. The ...
Bio & Medicine
Jul 18, 2022
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276
Chinese researchers recently reported an innovative mechanical process for controllably exfoliating hexagonal boron nitride nanosheets (h-BNNSs).This method, known as the "water-icing triggered exfoliation process," was proposed ...
Nanophysics
Jun 16, 2022
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119
A team of researchers affiliated with multiple institutions in the Republic of Korea working with a colleague from the University of Cambridge, has developed a way to use chemical-vapor deposition to build five layered single-crystal ...
Owing to their unique permeable, hollow shell structures with inner, movable cores, yolk-shell nanocrystals are suitable for a wide variety of applications. Yolk-shell nanocrystals consisting of a gold core with various semiconductor ...
Nanomaterials
Jun 7, 2022
0
93
Biomarkers are components that may be present in biological samples and are related to specific diseases. Therefore, doctors can analyze biological samples from a patient to check their health condition or to monitor the ...
Bio & Medicine
May 18, 2022
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112
Diamond nanocrystals, namely nanodiamonds, which host point defects such as nitrogen-vacancy (NV) centers, are a promising quantum material.
Nanophysics
Apr 27, 2022
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223
Two-dimensional (2D) transition metal dichalcogenides (TMDs), an emerging class of materials that can be used as semiconductors and insulators, have promising potential in various applications due to their unique properties. ...
Nanomaterials
Apr 20, 2022
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126
Graphene, which consists of a single layer of carbon atoms, is the poster child of carbon-based 2D nanomaterials. It has many attractive properties that could be exploited in next-generation electronics, optics, catalysis, ...
Nanomaterials
Mar 9, 2022
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172
2D van der Waals crystals, a class of materials that exhibit strong in-plane covalent bonds and weak interlayer interactions, have recently become the focus of numerous research studies due to their plethora of unique electrical, ...
Organohalides are widely adopted to serve as halide source in traditional three-precursors route to obtain metal halide perovskite nanocrystals (PNCs).
Nanomaterials
Jan 21, 2022
0
77
