Regeneration is a biological process by which organisms restore or replace lost or damaged tissues, organs, or body parts through controlled cell proliferation, differentiation, and patterning. It involves activation of resident stem or progenitor cells, dedifferentiation of mature cells in some taxa, and re-establishment of appropriate positional information via morphogen gradients and signaling pathways such as Wnt, FGF, BMP, and Notch. Regeneration can be epimorphic, with blastema formation and large-scale pattern reconstruction, or morphallactic, involving extensive tissue remodeling. Its extent and fidelity are species- and tissue-specific, constrained by genetic programs, immune responses, and age-dependent changes in cellular plasticity.
Scientists at the University of Helsinki discovered how plants heal their protective outer layer, the periderm. The diffusion of ethylene and oxygen through a wound triggers repair—a finding with potential implications for ...
Plants & Animals
Jul 2, 2025
0
164
A study by Children's Medical Research Institute (CMRI) researchers reveals a new group of proteins that guide the powerful enzyme telomerase, opening potential doors to novel treatments for cancer, aging, and genetic diseases.
Cell & Microbiology
Jul 2, 2025
0
35
Research led by the National Institute of Biological Sciences in Beijing has discovered that switching on a single dormant gene enables mice to regenerate ear tissue.
Regeneration, the ability to heal damaged or lost tissues, is both an everyday and a real-life superpower. Health research inspired by the remarkable regeneration of animals like axolotls or starfish asks how future therapeutics ...
Molecular & Computational biology
Jun 24, 2025
0
70
Zebrafish have the remarkable and rare ability to regrow and repair their hearts after damage. New research from Caltech and UC Berkeley has identified the circuit of genes controlling this ability and offers clues about ...
Cell & Microbiology
Jun 24, 2025
0
27
Mesenchymal stem cells (MSCs), which can be harvested from fat and bone marrow, have immune-modulating and anti-inflammatory effects that are beneficial for both human and veterinary medicine. However, MSCs have a limited ...
Biotechnology
Jun 20, 2025
0
62
Tiny gel droplets enhanced with University of Queensland technology could open new pathways to repairing and replacing damaged organs.
Biotechnology
Jun 19, 2025
0
22
Northwestern Medicine scientists have discovered how cells responsible for hair growth perceive physical forces in their environment and utilize that information to regulate their growth, according to a study published in ...
Cell & Microbiology
Jun 17, 2025
0
38
Axolotls are known for their ability to regrow limbs, organs and even parts of the brain and heart. But the tailed amphibian with the scientific name Ambystoma mexicanum can do even more. Its mucous membrane protects it from ...
Cell & Microbiology
Jun 17, 2025
0
168
Axolotls, with their signature smiles and pink gills, are the celebrities of the salamander world. But they are more than just cute: They might also hold the secret to regenerating human limbs.
Plants & Animals
Jun 10, 2025
0
85
