Regeneration is a biological process by which organisms restore or replace lost or damaged tissues, organs, or body parts through controlled cell proliferation, differentiation, and patterning. It involves activation of resident stem or progenitor cells, dedifferentiation of mature cells in some taxa, and re-establishment of appropriate positional information via morphogen gradients and signaling pathways such as Wnt, FGF, BMP, and Notch. Regeneration can be epimorphic, with blastema formation and large-scale pattern reconstruction, or morphallactic, involving extensive tissue remodeling. Its extent and fidelity are species- and tissue-specific, constrained by genetic programs, immune responses, and age-dependent changes in cellular plasticity.
A joint research team from POSTECH and Inha University researchers has successfully developed a novel biomaterial that overcomes the limitations of natural elastin.
Biotechnology
Sep 15, 2025
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Investigators at Johns Hopkins Medicine report new evidence that the protein Piezo1 controls skin growth by detecting when skin is stretched and then coordinating the metabolic and immune changes necessary for growth. Experts ...
Cell & Microbiology
Sep 5, 2025
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Researchers at University of Tsukuba examined how twin organisms can emerge from a single fertilized egg by studying sea urchin embryos. Their findings revealed that when an early-stage embryo is split in half, each portion ...
Cell & Microbiology
Sep 5, 2025
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30
Common shrews are one of only a handful of mammals known to flexibly shrink and regrow their brains. This rare seasonal cycle, known as Dehnel's phenomenon, has puzzled scientists for decades. How can a brain lose volume ...
Plants & Animals
Sep 1, 2025
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35
When injured, cells have well-regulated responses to promote healing. These include a long-studied self-destruction process that cleans up dead and damaged cells as well as a more recently identified phenomenon that helps ...
Cell & Microbiology
Aug 28, 2025
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63
Studying plant vegetative reproduction is key to increasing crop yield and for bioengineering. Kobe University research is making progress in studying the genetic regulation of the process in liverworts, which are ideal model ...
Plants & Animals
Jul 30, 2025
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37
Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, ...
Cell & Microbiology
Jul 21, 2025
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26
While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ears are damaged, the ...
Cell & Microbiology
Jul 14, 2025
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74
Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune system. The new approach, ...
Cell & Microbiology
Jul 3, 2025
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31
Cell sheet preparation for use in tissue engineering and regenerative therapies could be significantly improved with the use of thermo-responsive polymer brushes, adjusted in length and density according to specific cell ...
Cell & Microbiology
Jul 3, 2025
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