Organs are anatomically distinct structural and functional units within multicellular organisms, composed of multiple tissue types organized to perform specific physiological roles as part of larger integrated physical systems. Each organ exhibits characteristic morphology, vascularization, innervation, and cellular specialization that enable processes such as filtration, secretion, contraction, signal transduction, or exchange of gases and nutrients. Organs interact through coordinated biochemical, mechanical, and electrical signaling within organ systems to maintain homeostasis, support development, and enable adaptive responses. In systems biology and physiology, organs are modeled as complex, hierarchically organized physical systems with emergent properties arising from tissue-level and cellular interactions.
Organoids are three-dimensional miniature models of organs, grown in a dish. They have become a valuable tool for studying human development, organ regeneration, function, and disease progression. Organoids derived from patient ...
Cell & Microbiology
Jan 21, 2026
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23
New research has mapped the cell types that specialize to form reproductive organs in both sexes, identifying key genes and signals that drive this process. The findings offer important insights into conditions affecting ...
Cell & Microbiology
Dec 17, 2025
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16
Biological sex is usually described in simple binary terms: male or female. This works well for germ cells (sperm versus eggs), but for other body organs it is of little help.
Evolution
Sep 18, 2025
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311
Organ donors can save lives, for example, those of patients with kidney failure. Unfortunately, there are too few donors, and the waiting lists are long. 3D bioprinting of (parts of) organs may offer a solution to this shortage ...
Biotechnology
Sep 5, 2025
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68
Studying the process of brain formation illuminates just how much of development is a series of tiny miracles. Only a few weeks after a human egg is fertilized, a sheet of cells called the neural plate widens, stretches and ...
Cell & Microbiology
Aug 21, 2025
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36
In the past, scientists believed that the fast-acting biochemistry of genes and proteins was responsible for directing the forces that shape developing organs. But a new study from Syracuse University shows that steady, powerful ...
Molecular & Computational biology
Aug 21, 2025
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One of the most fundamental processes in all of biology is the spontaneous organization of cells into clusters that divide and eventually turn into shapes—be they organs, wings or limbs.
Cell & Microbiology
Aug 21, 2025
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42
Scientists have found a way to visualize delicate organs like the brain and heart by letting light into the tissues and exposing their inner workings, no dissection required. In their study published in Cell, Chinese researchers ...
Bioengineered organs are no longer just structural substitutes. A review published in Trends in Biotechnology introduces a groundbreaking concept: biohybrid-engineered tissue (BHET) platforms—living constructs integrated ...
Biotechnology
Jul 18, 2025
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30
A new study by scientists at the University of North Carolina at Chapel Hill reveals that the cells shaping our organs may be far more mobile and coordinated than once believed. The study is published in the journal Science ...
Cell & Microbiology
Jun 18, 2025
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