Organelle biogenesis is the biological process by which cells establish, maintain, and propagate their membrane-bound compartments, including their specific protein and lipid compositions, morphology, and copy number. It involves de novo formation from precursor membranes (e.g., ER-derived peroxisomes), growth and division of pre-existing organelles (e.g., mitochondria, chloroplasts), and tightly regulated trafficking of proteins and lipids via targeted import, vesicular transport, and membrane remodeling. Organelle biogenesis is coordinated with the cell cycle, metabolic state, and signaling pathways, relying on dedicated machineries such as translocases, coat proteins, small GTPases, and cytoskeletal elements to ensure fidelity of organelle identity and function across cell generations.
Inside every cell, thousands of proteins must reach the right place at the right time. Helping coordinate this complex logistics network are centriolar satellites—tiny, membraneless organelles that play important roles in ...
Cell & Microbiology
Aug 20, 2026
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Our DNA is under constant threat. Chemicals, radiation and the everyday errors of cell division all damage it, and if left unrepaired, this can lead to diseases such as cancer. Cells invest heavily in finding and fixing these ...
Molecular & Computational biology
Jul 30, 2026
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16
In a study published in Nature Communications, researchers at Karolinska Institutet have mapped key steps in the assembly of the mitochondrial ribosome, offering new clues to how defects in this process can lead to disease.
Cell & Microbiology
Jun 24, 2026
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A new study reveals the dynamics of photosynthesis at the cellular level. Led by co-authors Professor Barry Bruce and Associate Professor Rajan Lamichhane, both of the Department of Biochemistry and Cellular and Molecular ...
Cell & Microbiology
Jun 23, 2026
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A new study provides the first insights into how thylakoid membranes—the internal compartments where oxygen-producing photosynthesis takes place—emerged during evolution. By comparing the genomes of cyanobacteria with and ...
Evolution
Jun 22, 2026
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For decades, science has understood the basics of photosynthesis, the process by which plants turn sunlight into food. However, photosynthesis occurs on uniquely specialized membranes that we have only begun to understand. ...
Plants & Animals
Jun 9, 2026
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For most of their lives, plants get their energy from photosynthesis. But during the seed to seedling stage, when they can't absorb light just yet, they rely on other sources, like fatty acids. To process the fatty acids, ...
Molecular & Computational biology
Apr 27, 2026
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15
A new study conducted by researchers from the University of Potsdam and the University of Cologne has deciphered the step-by-step assembly of the eukaryotic proteasome. Eukaryotes are organisms whose cells have a clearly ...
Cell & Microbiology
Mar 24, 2026
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8
After a heart attack, the heart struggles to recoup and maintain energy. One-third of patients develop heart failure as a result—a condition that impacts 6.8 million Americans and carries a high lifetime risk, with 1 in 4 ...
Cell & Microbiology
Mar 9, 2026
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46
A new study has uncovered a hidden step that helps the deadliest malaria parasite survive and multiply inside the human body. Researchers studying Plasmodium falciparum found that the parasite relies on a brief but essential ...
Cell & Microbiology
Feb 4, 2026
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