Immunology is the scientific discipline that investigates the molecular, cellular, and systemic mechanisms underlying immune recognition, regulation, and effector function in vertebrates and other organisms. It encompasses the study of innate and adaptive immune responses, including antigen processing and presentation, clonal selection, tolerance, immune memory, and the cytokine networks that orchestrate these processes. Immunology also examines the pathophysiology of immune-mediated diseases such as autoimmunity, allergy, immunodeficiencies, and transplant rejection, and underpins the rational design of vaccines, monoclonal antibodies, immunotherapies, and diagnostic assays through quantitative, genetic, and systems-level approaches.
A class of ultrasmall fluorescent core-shell silica nanoparticles developed at Cornell is showing an unexpected ability to rally the immune system against melanoma and dramatically improve the effectiveness of cancer immunotherapy, ...
Bio & Medicine
Jan 5, 2026
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Immune checkpoint molecules play a crucial role in keeping the immune system in balance and preventing an attack on the body's own cells. Cancer cells can use these checkpoints to hide from the immune system, making them ...
Bio & Medicine
Jan 5, 2026
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Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor. A KAIST research team led by Professor ...
Bio & Medicine
Jan 2, 2026
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Immunotherapy has emerged in recent years as a new cancer treatment that is gentler than traditional chemotherapy and causes milder side effects in patients. However, conventional dendritic cell (DC) immunotherapy shows inconsistent ...
Bio & Medicine
Dec 30, 2025
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A new study from North Carolina State University found that neutrophils—white blood cells that are a key part of the immune system—play a role in the early stages of atopic dermatitis flares in dogs. The work is a first step ...
Veterinary medicine
Dec 17, 2025
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Researchers Sumika Kato, Takeo Kubo, and Taro Fukazawa of the University of Tokyo have discovered that c1qtnf3, a secreting factor, namely a protein molecule that is secreted by a cell and influences functions of other cells, ...
Cell & Microbiology
Nov 17, 2025
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When pathogens enter our cells as part of an infection, our body will trigger a programmed cell death known as "pyroptosis" as part of an antimicrobial response. This response also plays a role in processes which are not ...
Cell & Microbiology
Nov 4, 2025
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18
Temperature is a key physiological factor that determines the speed of immune reactions. While this may seem obvious, it has remained largely unexplored at the single-cell level—until now. Stefan Wieser from the Institute ...
Cell & Microbiology
Nov 4, 2025
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24
A multi-institutional team led by University of Washington scientists have engineered a new vaccine platform combining mRNA and computational protein design, producing in mice a potent immune defense against both Wuhan-Hu-1 ...
A research team has introduced a novel cancer immunotherapy strategy. This approach involves attaching "fake targets" to tumor cells to guide immune cell attacks, overcoming the limitations of conventional antibody-based ...
Bio & Medicine
Oct 16, 2025
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