Immune evasion is a biological process by which pathogens, tumor cells, or other aberrant cells avoid detection, recognition, or elimination by the host immune system, thereby promoting persistence and proliferation. Mechanisms include antigenic variation, downregulation or loss of major histocompatibility complex (MHC) molecules, expression of immune checkpoint ligands (e.g., PD-L1), secretion of immunosuppressive cytokines, induction of regulatory T cells or myeloid-derived suppressor cells, and shielding of antigens within biofilms or physical barriers. This process critically influences infection chronicity, tumor progression, vaccine efficacy, and the outcome of host–pathogen or host–tumor coevolution.
Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells. However, most genetic disorders are caused by dozens or even thousands of unique mutations spread ...
Biotechnology
Mar 11, 2026
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It infects nearly one-third of the global population, yet its microscopic size makes the parasite difficult for scientists to study. That parasite is Toxoplasma gondii, a widespread organism that infects humans and animals. ...
Cell & Microbiology
Mar 6, 2026
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71
The cold season is in full swing, throats are scratchy and noses are running. We feel ill and hope it is not the flu. The influenza virus continues to pose a threat to our health. It triggers seasonal epidemics and, from ...
Cell & Microbiology
Mar 4, 2026
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Hepatitis C virus (HCV) infects an estimated 50 million people worldwide, according to the World Health Organization, and remains a leading cause of cirrhosis and liver cancer. While antiviral drugs can cure most infections, ...
Bio & Medicine
Mar 4, 2026
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Research on preventing type 1 diabetes often focuses on limiting the autoimmune response that destroys the body's ability to produce its own insulin. A new technology developed by scientists at the University of Chicago takes ...
Bio & Medicine
Mar 1, 2026
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82
Our bodies are home to millions of fungi that, for the most part, are completely harmless. However, they can sometimes change from peaceful residents into dangerous invaders. One such is Candida parapsilosis, which normally ...
Scientists have uncovered an elegant biophysical trick that tuberculosis-causing bacteria use to survive inside human cells, a discovery that could lead to new strategies for fighting one of the world's deadliest infectious ...
Cell & Microbiology
Feb 21, 2026
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103
Most bacteria, including many bacterial pathogens, are surrounded by an outer protective layer of sugar molecules, known as a capsule. This primarily protects the bacteria from environmental influences, but also serves as ...
Cell & Microbiology
Feb 16, 2026
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94
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent ...
Cell & Microbiology
Feb 12, 2026
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153
New research led by the University of East Anglia (UEA) shows how many tropical cities are predicted to warm faster than expected under 2°C of global warming.
Environment
Feb 4, 2026
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