Host-pathogen interactions are the dynamic, reciprocal biological processes that occur between a host organism and an invading pathogen, encompassing molecular recognition, immune sensing, signaling, and effector responses, as well as pathogen strategies for attachment, invasion, replication, and immune evasion. These interactions involve pattern recognition receptors (e.g., Toll-like, NOD-like, and RIG-I-like receptors), pathogen-associated molecular patterns, and downstream signaling pathways that regulate inflammation, cell death, and antimicrobial defenses. Concurrently, pathogens deploy virulence factors, secretion systems, and immune-modulatory molecules to manipulate host cell pathways, subvert immunity, and optimize their survival, replication, and transmission, thereby determining infection outcomes and disease pathogenesis.
Researchers from Skoltech—a VEB.RF group institution—and their colleagues from the U.S. and China have explained how the antibiotic resistance gene established itself in the genome of the bacterium Klebsiella pneumoniae. ...
Cell & Microbiology
Jun 10, 2026
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Researchers at the Helmholtz Institute for One Health (HIOH) have demonstrated that larvae of the greater wax moth, Galleria mellonella, are suitable as an alternative infection model for investigating the pathogenicity of ...
Plants & Animals
Jun 8, 2026
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A new study from the University of Kentucky Martin-Gatton College of Agriculture, Food and Environment (CAFE) helps explain how plants can lose track of their own disease warnings.
Plants & Animals
Jun 3, 2026
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UCF College of Medicine Assistant Professor Renee Fleeman continues to refine a powerful therapy for drug-resistant bacteria that pierces the gooey coating that anchors and protects such germs from the drugs we take to kill ...
Cell & Microbiology
Jun 3, 2026
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A new predictive model developed at Washington State University could help scientists more efficiently identify the reservoirs of emerging zoonotic viruses and dangerous pathogens like Ebola that can spill over from animals ...
Veterinary medicine
Jun 3, 2026
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Research into a common environmental germ that can cause severe infections in people and animals has raised concern that horses are starting to develop antibiotic resistance towards it. The University of the Sunshine Coast ...
Molecular & Computational biology
Jun 2, 2026
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Even though sugars are often framed as simple sources of energy, they also serve as structurally complex and functionally diverse molecules that mediate interactions between organisms. Among these, β-1,2-glucans, which are ...
Cell & Microbiology
May 31, 2026
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When viruses invade a plant, you might expect an all-out immune war. But new research published in Science shows that, much like in humans, too strong an immune response can actually do more harm than good.
Cell & Microbiology
May 29, 2026
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Researchers have found surprising links that show that Neanderthal ancestry influences our immune system today in ways more nuanced than previously recognized. Their work is published in the journal Genome Biology and Evolution.
Evolution
May 28, 2026
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493
Johanna Harvey, an assistant professor of wildlife disease ecology at the University of Rhode Island, has described bird flu in public presentations as a quiet virus with loud consequences. Now, she's published a new paper ...
Ecology
May 27, 2026
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