Host-pathogen interactions are the dynamic, reciprocal biological processes that occur between a host organism and an invading pathogen, encompassing molecular recognition, immune sensing, signaling, and effector responses, as well as pathogen strategies for attachment, invasion, replication, and immune evasion. These interactions involve pattern recognition receptors (e.g., Toll-like, NOD-like, and RIG-I-like receptors), pathogen-associated molecular patterns, and downstream signaling pathways that regulate inflammation, cell death, and antimicrobial defenses. Concurrently, pathogens deploy virulence factors, secretion systems, and immune-modulatory molecules to manipulate host cell pathways, subvert immunity, and optimize their survival, replication, and transmission, thereby determining infection outcomes and disease pathogenesis.
An international research team led by Cologne-based plant scientist Professor Dr. Bart Thomma from the Institute for Plant Sciences, the Collaborative Research Center MiBiNet and the CEPLAS Cluster of Excellence for Plant ...
Cell & Microbiology
Apr 30, 2026
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A research team from the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has developed a machine-learning classifier capable of analyzing the genomes of influenza A viruses (IAVs) to accurately predict their ...
Cell & Microbiology
Apr 29, 2026
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How are bacterial pathogens able to effectively overcome plants' defense mechanisms? Researchers working with Professor Şuayb Üstün at Ruhr University Bochum, Germany, have found a surprising answer to this question: The ...
Plants & Animals
Apr 27, 2026
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During infection, pathogens must adapt quickly to the conditions to thrive inside the body. A research team at the University of Basel, Switzerland, has uncovered how a key protein switches on the machinery that enables Leptospira ...
Cell & Microbiology
Apr 27, 2026
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Scientists have mapped in unprecedented detail the structure of Vibrio bacteria, which can cause life-threatening infections linked to antibiotic resistance. The King's College London team behind the study, published in Nature ...
Cell & Microbiology
Apr 25, 2026
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48
Despite decades of efforts to combat it, malaria remains a major global health threat. According to the World Health Organization's (WHO) 2025 World Malaria Report, about 282 million cases and approximately 610,000 deaths ...
Molecular & Computational biology
Apr 21, 2026
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13
Researchers at Umeå University have identified two human cell proteins, NUP98 and NUP153, that play a crucial role in how viruses such as tick-borne encephalitis virus (TBEV), West Nile virus, and dengue virus replicate in ...
Cell & Microbiology
Apr 21, 2026
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Researchers have developed a new artificial intelligence (AI) model that can more accurately predict how proteins interact with one another—an advancement that could accelerate drug discovery and deepen insights into diseases ...
Biotechnology
Apr 20, 2026
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University of California San Diego researchers have developed a new tool for understanding and modifying any microbiome, including the human microbiome. The approach, called Microbial Interaction and Niche Determination (MIND), ...
Cell & Microbiology
Apr 20, 2026
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32
Maintaining connections between natural habitats may support beneficial microbes that help wildlife defend against disease. In a new study of tropical amphibians, a team led by Penn State biologists found that amphibians ...
Ecology
Apr 20, 2026
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