Research news on Genomes

Genomes, as physical systems, comprise the complete set of nucleic acid molecules (typically DNA, or RNA in some viruses) that encode the hereditary information of an organism, including all chromosomes and extrachromosomal genetic elements. They are organized into linear or circular polymers of nucleotides, with specific higher-order structures such as chromatin in eukaryotes or nucleoid organization in prokaryotes. At the physical level, genomes exhibit defined sequence composition, length, and structural features (e.g., replication origins, regulatory regions, repetitive elements) that collectively determine their stability, replication dynamics, mutational patterns, and interactions with cellular molecular machinery.

AI decodes plant DNA 'switches' to better predict gene control

An international research team led by Forschungszentrum Jülich and the IPK Leibniz Institute has developed an artificial intelligence model that predicts where regulatory proteins dock onto plant DNA to switch genes on and ...

Genomes from Oceania offer new clues to human evolution

A new Yale-led study provides one of the most detailed and comprehensive analyses to date of genetic variation in human populations in Oceania, filling a major gap in representation in genomics research. Despite harboring ...

Why are sloths slow? It's in their DNA

Sloths are the slowest mammals on the planet, but living in dense jungles has made them notoriously difficult to study. For the first time, scientists have now sequenced and analyzed the two-toed sloth genome and revealed ...

Why does the Y chromosome retain UTY?

A study, published in the journal Development, is the first to precisely map endogenous UTY occupancy across the human genome and demonstrate that UTY remains functionally involved in transcriptional regulation during early ...

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