Molecular evolution is the biological process encompassing changes in the nucleotide sequences of DNA or RNA and the amino acid sequences of proteins over time, driven by mutation, recombination, genetic drift, natural selection, and other population-level forces. It focuses on the rates and patterns of substitutions, insertions, deletions, and genome rearrangements, as well as the emergence of new genes and regulatory elements. Molecular evolution underlies divergence among species, functional innovation, and conservation of essential biomolecules, and is quantitatively analyzed using models of sequence evolution, comparative genomics, and phylogenetic inference to elucidate evolutionary relationships and constraints at the molecular level.
Enzymes catalyze chemical reactions in organisms—without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité—Universitätsmedizin Berlin have now succeeded in analyzing the ...
Evolution
Jul 9, 2025
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25
A team of researchers has developed a method that could transform the field of protein engineering. The new approach, called AI-informed Constraints for protein Engineering (AiCE), enables rapid and efficient protein evolution ...
Biotechnology
Jul 8, 2025
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34
Two species of worms have retained remarkably similar patterns in the way they switch their genes on and off despite having split from a common ancestor 20 million years ago, a new study finds.
Evolution
Jun 19, 2025
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98
In football, defense keeps the opposing team in check. A similar strategy is at play inside our cells. Negative feedback loops (NFLs) help regulate how cells respond to signals, for example, dialing down activity when things ...
Evolution
Jun 13, 2025
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43
Researchers have found that chunks of "flipped" DNA can help fish quickly adapt to new habitats and evolve into new species, acting as evolutionary "superchargers."
Evolution
Jun 12, 2025
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62
Genetic changes can occur naturally through evolution or can be initiated with the help of genetic engineering. The bacterium Thermoanaerobacter kivui (T. kivui) was manipulated by a research team led by Stefan Pflügl from ...
Cell & Microbiology
Jun 12, 2025
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28
By attaching molecules together, scientists at Université de Montréal think they've found how molecular systems at the origin of life evolved to create complex self-regulating functions.
Bio & Medicine
Feb 7, 2024
1
261
Richard Feynman famously stated, "Everything that living things do can be understood in terms of the jigglings and wigglings of atoms." This week, Nature Nanotechnology features a study that sheds new light on the evolution ...
Bio & Medicine
Nov 27, 2023
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