DNA sequencing is a set of laboratory methods for determining the precise linear order of nucleotides (A, C, G, T) in a DNA molecule. Core methodological classes include Sanger sequencing, which uses chain-terminating dideoxynucleotides and capillary electrophoresis for high-fidelity, low-throughput analysis, and next-generation sequencing (NGS) platforms, which employ massively parallel sequencing-by-synthesis, sequencing-by-ligation, or nanopore-based readout for high-throughput, genome-scale applications. These methods entail library preparation, clonal or single-molecule amplification (except in true single-molecule approaches), signal detection, and computational base-calling, followed by quality control and downstream bioinformatic analysis.
An international team of scientists has recreated a 1,000-year timeline documenting ecological changes and human impact on the area surrounding Crawford Lake, the famed location of the proposed Anthropocene.
Ecology
Sep 9, 2026
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24
Shark products sold at Western Australian fish-and-chips shops are often labeled too ambiguously or, in some cases, mislabeled, leaving consumers unsure which species they are buying, new Murdoch University research shows.
Ecology
Sep 2, 2026
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17
Fast, on-farm genetic testing for cattle is practical and achievable for northern producers, according to University of Queensland research. In partnership with Meat & Livestock Australia and the Department of Primary Industries, ...
Molecular & Computational biology
Aug 31, 2026
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8
Atlantic herring travel in massive schools that can contain hundreds of millions—and sometimes even billions—of fish. While this abundance is characteristic of one of the most successful vertebrates on Earth, it also creates ...
Plants & Animals
Aug 31, 2026
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17
Researchers at the University of Eastern Finland and the University of Oulu have produced the first chromosome-level reference genome for the Saimaa ringed seal. The sequence of every chromosome in the seal's entire genome ...
Plants & Animals
Aug 26, 2026
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7
Scientists have identified an unexpected source of genetic variation in human sperm that occurs earlier in sperm development than previously thought. Published in Nature, researchers at the Wellcome Sanger Institute, the ...
Cell & Microbiology
Aug 26, 2026
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663
Can DNA traces in just two liters (0.5 gallons) of water reveal how a river's biodiversity changes over the course of a year? A study by the University of Duisburg-Essen using the River Lippe as an example shows how biodiversity ...
Ecology
Aug 26, 2026
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7
The Land Institute and HudsonAlpha Institute for Biotechnology, in collaboration with key partners, have assembled the first chromosome-scale, haplotype-phased genomes for Silphium integrifolium (rosinweed, silflower) and ...
Molecular & Computational biology
Aug 24, 2026
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10
A mule has helped researchers build the most complete reference genomes to date for horses and donkeys, giving scientists access to complex regions of DNA that earlier versions could not fully capture.
Evolution
Aug 24, 2026
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48
Precise activation of tens of thousands of genes is critical for healthy development and growth. Specialized segments of our DNA are responsible for carefully orchestrating genetic sequences that result in the production ...
Biotechnology
Aug 22, 2026
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