Page 7: Research news on Biomolecular & subcellular processes

Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.

Four-decade mystery solved as PKCβ structure reveals new drug target

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structure of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases. The findings, published in Nature ...

Video: How are we so good at folding proteins?

Proteins carry out almost every important function in our body, from copying our DNA to turning the food we eat into energy. These tiny "molecular machines" are first made by our cells as straight chains, like long pieces ...

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