Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
Cell membranes cradle, protect, and gatekeep living cells. Membranes can even affect how a cell behaves.
Bio & Medicine
Aug 1, 2025
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84
Proteins sustain life as we know it, serving many important structural and functional roles throughout the body. But these large molecules have cast a long shadow over a smaller subclass of proteins called microproteins.
Biotechnology
Jul 31, 2025
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178
A KAIST research team led by Professor Won Do Heo (Department of Biological Sciences) has developed an optogenetic platform, RELISR (REversible LIght-induced Store and Release), that enables precise spatiotemporal control ...
Biotechnology
Jul 28, 2025
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23
Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, modulating the ability of ribosomes ...
Biotechnology
Jul 25, 2025
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46
Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are built from 20 different types of amino acid molecules, so even a small protein made of 60 amino acids ...
Molecular & Computational biology
Jul 24, 2025
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198
The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's. But to the human eye, proteins that are destined to form harmful ...
Cell & Microbiology
Jul 24, 2025
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90
In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic "map" of how cells orchestrate glucose processing, revealing a hidden world ...
Cell & Microbiology
Jul 21, 2025
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83
Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene regulation lack stable structure. ...
Molecular & Computational biology
Jul 21, 2025
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30
In every living cell, there are membranes, and in every membrane there are proteins, each of which acts as a chemical gatekeeper.
Bio & Medicine
Jul 21, 2025
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66
Scientists have discovered a new way to advance drug discovery and diagnostics by targeting a part of the proteome (the complete set of proteins in an organism) that was previously thought inaccessible to drug development, ...
