Page 29: Research news on Biomolecular & subcellular processes

Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.

DNA shape and rigidity regulate key players of gene expression

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the physical structure and shape ...

Watching DNA repair in real time with a live-cell sensor

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and repair unfold in real ...

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