Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
A new tool developed by Helmholtz Munich and the German Center for Diabetes Research and the University of Bonn makes spatial proteomics and lipidomics easier to use—no coding required. C-COMPASS allows scientists to profile ...
Cell & Microbiology
Dec 4, 2025
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16
Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. Once considered mere transcriptional noise, lncRNAs are now known to play vital roles in plant growth, development, ...
Plants & Animals
Dec 3, 2025
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14
A team of researchers from Academia Sinica and National Taiwan University has identified the Drosophila Cul2 substrate adaptor DmZer1 as a key regulator of protein quality control, acting at the intersection of two major ...
Molecular & Computational biology
Dec 2, 2025
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15
At European XFEL, researchers have observed in detail how the vital iron protein ferritin makes its way in highly dense environments—with implications for medicine and nanotechnology.
Biotechnology
Dec 2, 2025
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20
mRNA, widely known from the COVID-19 vaccine, is not actually a "therapeutic agent," but a technology that delivers the blueprint for functional proteins in the body and induces therapeutic effects. Recently, its application ...
Biotechnology
Dec 2, 2025
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17
New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA mismatch repair, a process ...
Molecular & Computational biology
Dec 2, 2025
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14
The ability to self-organize is a key feature of biological systems and is widely found in nature: small building blocks that autonomously assemble give rise to macromolecules such as the cell nucleus, virus capsids, or complex ...
Cell & Microbiology
Dec 1, 2025
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14
A new study describes a key molecular mechanism that explains how cells exchange information through extracellular vesicles (EVs), small particles with great therapeutic potential. The results, published in the Journal of ...
Cell & Microbiology
Nov 28, 2025
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15
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study published in Nature Communications ...
Biotechnology
Nov 27, 2025
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94
Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists know that Pol II must ...
Cell & Microbiology
Nov 27, 2025
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