Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders—including cancers, neurodegenerative diseases and immune disorders—originate, as well as how to ...
Cell & Microbiology
Dec 16, 2025
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20
Conditions can get rough in the micro- and nanoworld. For example, to ensure that nutrients can still be optimally transported within cells, the minuscule transporters involved need to respond to the fluctuating environment. ...
General Physics
Dec 15, 2025
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41
During early development, tissues and organs begin to bloom through the shifting, splitting, and growing of many thousands of cells.
Cell & Microbiology
Dec 15, 2025
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132
Liquids and solutions are complex environments—think, for example, of sugar dissolving in water, where each sugar molecule becomes surrounded by a restless crowd of water molecules. Inside living cells, the picture is even ...
Optics & Photonics
Dec 14, 2025
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126
Dynamin is a protein that plays a central role in endocytosis—the process where cells internalize substances by wrapping them in cell membrane vesicles. For a vesicle to detach, the neck of the membrane must be constricted ...
Cell & Microbiology
Dec 10, 2025
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16
Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, revealing how this essential ...
Cell & Microbiology
Dec 10, 2025
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138
For numerous fundamental processes of life, the formation of certain protein patterns is essential. Protein pattern formation controlled by molecular switches is—like many processes in nature—far removed from a state of equilibrium.
Soft Matter
Dec 8, 2025
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40
Microtubules perform an active role in communication within the cell by transmitting received signals to the cell's functional units. Researchers at the Paul Scherrer Institute PSI and the Department of Biomedicine at the ...
Cell & Microbiology
Dec 8, 2025
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111
While synchrotron radiation is often thought of as "stable," the electromagnetic field exhibits pronounced randomly fluctuating distributions both temporally and spatially. These fluctuations encode spatial information about ...
Optics & Photonics
Dec 5, 2025
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49
All cells need to sense and respond to their environment, to know when to activate genes, build proteins, and carry out their basic functions. One of the most well-studied cellular responses is how they react during times ...
Cell & Microbiology
Dec 4, 2025
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55
