Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
Through cutting-edge methods and advanced artificial intelligence analysis, UNC Charlotte researchers leading a multidisciplinary team across four universities have successfully resolved the entire genome of "Phage G," the ...
Cell & Microbiology
Oct 29, 2025
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63
Metagenomics is the study of all organisms present in a particular environment, such as soil, water, or the human body. A key part of metagenomic analysis is understanding what species are present (classification), how much ...
Cell & Microbiology
Oct 27, 2025
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18
Cellarity, a biotechnology company developing cell state-correcting therapies through integrated multi-omics and AI modeling, reports the publication of a manuscript in the journal Science, which articulates a framework for ...
Cell & Microbiology
Oct 23, 2025
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27
In the hunt for new therapeutics for cancer and infectious diseases, lasso peptides prove to be a catch. Their knot-like structures afford these molecules high stability and diverse biological activities, making them a promising ...
Biotechnology
Oct 16, 2025
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35
Every organism's genome contains mutations that often have unknown biological effects. In partnership with Stanford University, researchers at Charité—Universitätsmedizin Berlin have now discovered a way to predict the effects ...
Cell & Microbiology
Oct 10, 2025
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29
Researchers at University of Tsukuba have developed DeMemSeg, an AI-powered analysis pipeline that addresses a long-standing challenge in microscopy: precisely segmenting and measuring individual cell membranes that overlap ...
Cell & Microbiology
Oct 8, 2025
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17
By making the world's microbial DNA easier to explore, a new sequence alignment tool, LexicMap, lets scientists search for a DNA sequence against millions of bacterial and archaeal genomes in minutes, helping researchers ...
Biotechnology
Sep 30, 2025
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23
Population bottlenecks caused by stark population loss due to illness or habitat destruction caused mammals' disease immunity to decline, according to a new study led by computational biologists in the Penn State School of ...
Evolution
Sep 30, 2025
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22
Scientists from James Cook University have developed a new computer tool that reveals layers of gene activity that were previously invisible, opening fresh possibilities for understanding health and disease.
Biotechnology
Sep 25, 2025
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15
An international team of scientists, including from Rothamsted Research, have developed a new method to improve the accuracy of gene mapping in complex organisms—a breakthrough that could enhance research into fungal diseases ...
Molecular & Computational biology
Sep 23, 2025
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22
