Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
Researchers at North Carolina State University have developed a new suite of statistical methods that dramatically improves the ability to pinpoint DNA changes responsible for important traits in livestock. The work addresses ...
Molecular & Computational biology
Dec 4, 2025
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30
A new tool developed by Helmholtz Munich and the German Center for Diabetes Research and the University of Bonn makes spatial proteomics and lipidomics easier to use—no coding required. C-COMPASS allows scientists to profile ...
Cell & Microbiology
Dec 4, 2025
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1
Researchers have developed VIRE, a database that integrates approximately 1.7 million viral genomes derived from more than 100,000 metagenomes worldwide. Metagenomic data is obtained by comprehensively sequencing all DNA ...
Molecular & Computational biology
Dec 1, 2025
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11
Researchers from Turku Bioscience Center at the University of Turku, Finland, have developed a new computational method to interpret complex single-cell data. The method helps researchers identify and group cell types across ...
Cell & Microbiology
Nov 17, 2025
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Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases. Analyzing these datasets ...
Cell & Microbiology
Nov 11, 2025
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49
Researchers from the University of Eastern Finland and Aalto University have developed a computational framework called SegPore that enhances the accuracy of RNA modification detection from direct RNA nanopore sequencing ...
Biotechnology
Nov 6, 2025
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With a newly developed method that compares AI-generated protein sequences with naturally occurring ones, function- and structure-regulating amino acids can be determined much more precisely than before.
Biotechnology
Oct 30, 2025
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28
Through cutting-edge methods and advanced artificial intelligence analysis, UNC Charlotte researchers leading a multidisciplinary team across four universities have successfully resolved the entire genome of "Phage G," the ...
Cell & Microbiology
Oct 29, 2025
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3
Metagenomics is the study of all organisms present in a particular environment, such as soil, water, or the human body. A key part of metagenomic analysis is understanding what species are present (classification), how much ...
Cell & Microbiology
Oct 27, 2025
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0
Cellarity, a biotechnology company developing cell state-correcting therapies through integrated multi-omics and AI modeling, reports the publication of a manuscript in the journal Science, which articulates a framework for ...
Cell & Microbiology
Oct 23, 2025
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