Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and overlooks experimental conditions ...
Biotechnology
22 hours ago
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22
Genome editing lets scientists rewrite DNA, the instruction manual inside every living cell, with a precision that was unthinkable a generation ago. Technologies such as CRISPR have made this almost routine, and its uses ...
Biotechnology
Jun 24, 2026
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25
How the proteins in our bodies bind together to form protein complexes plays a critical role in numerous cell functions—staving off diseases, for instance, or transporting ions across cell membranes. A better understanding ...
Molecular & Computational biology
Jun 24, 2026
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5
A new algorithm could drive breakthroughs in understanding cancer, Alzheimer's disease and other potentially fatal conditions. Researchers from the University of Waterloo developed the machine-learning algorithm, called RNovA, ...
Cell & Microbiology
Jun 23, 2026
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How does your body produce millions of antibodies from one genome? New research reveals how two closely related proteins help immune cells fold DNA, connecting distant genetic pieces to create diverse antibodies that help ...
Cell & Microbiology
Jun 23, 2026
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Researchers have identified "DNA switches" that become active as honeybee larvae grow into worker bees, offering new insight into the development of these important pollinators and the ecosystems they support.
Ecology
Jun 23, 2026
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11
A team of researchers led by Professor Akitsu Hotta (Department of Clinical Application) developed a comprehensive framework that combines computational prediction, experimental validation and whole-genome analysis to evaluate ...
Biotechnology
Jun 22, 2026
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9
New antibiotic candidates for drug-resistant bacteria may reside inside prions, misfolded proteins in the brain best known for rare and fatal degenerative brain diseases. Prion and prion-like proteins may hide short peptides, ...
Cell & Microbiology
Jun 19, 2026
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27
Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment has been the focus of a 30-year research question. New work from the Crick has recorded the missing ...
Cell & Microbiology
Jun 18, 2026
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8
Scientists studying lipids—the fatty molecules that store energy, make up cell membranes and act as signals—produce enormous amounts of information. A single experiment can detect thousands of different lipid molecules, generating ...
Biotechnology
Jun 18, 2026
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