Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
Phylo-Plex, a new computational method, has been developed by Wellcome Sanger Institute scientists and their collaborators to allow cost-effective and scalable DNA sequencing of pathogens in laboratories with limited resources. ...
Molecular & Computational biology
Jul 9, 2026
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19
RNA has emerged as one of the most promising molecules in modern medicine, enabling advances from mRNA vaccines and gene therapies to genome editing and synthetic biology. However, designing RNA molecules that reliably fold ...
Biotechnology
Jul 8, 2026
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9
In a paper published in Proceedings of the National Academy of Sciences, researchers from Technion and Tel Aviv University present BetaDescribe, an AI system that translates protein sequences into natural-language descriptions, ...
Biotechnology
Jul 6, 2026
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71
Decades-old hospital samples have helped University of East Anglia (UEA) researchers uncover how a deadly antibiotic-resistant "superbug" quietly tightened its grip across the globe. It lurked in hospital corridors for decades, ...
Evolution
Jul 1, 2026
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203
In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become integrated into ancient ...
Evolution
Jul 1, 2026
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17
Accurate RNA splicing is essential for gene expression and human health, yet predicting how DNA sequence variations affect splicing remains a major challenge. Although recent artificial intelligence (AI) models have improved ...
Biotechnology
Jun 30, 2026
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5
The same family of artificial intelligence that powers today's image generators is now being aimed at one of biology's hardest puzzles: the ever-changing, three-dimensional shapes of RNA. These are the molecules behind mRNA ...
Biotechnology
Jun 30, 2026
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27
The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and overlooks experimental conditions ...
Biotechnology
Jun 29, 2026
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45
Genome editing lets scientists rewrite DNA, the instruction manual inside every living cell, with a precision that was unthinkable a generation ago. Technologies such as CRISPR have made this almost routine, and its uses ...
Biotechnology
Jun 24, 2026
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28
How the proteins in our bodies bind together to form protein complexes plays a critical role in numerous cell functions—staving off diseases, for instance, or transporting ions across cell membranes. A better understanding ...
Molecular & Computational biology
Jun 24, 2026
0
6
