Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
A newly designed AI-powered tool is effective in developing treatments to attack antibiotic-resistant bacteria by breaking down their outer defenses, according to new research from Houston Methodist. The study, published ...
Cell & Microbiology
Apr 17, 2026
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A research team has discovered an enhanced CRISPR gene-editing system that could enable targeted delivery inside the human body—a key step toward broader clinical use. Researchers identified a naturally occurring enzyme, ...
Biotechnology
Apr 13, 2026
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The wave-shaped chart Ratul Chowdhury pulls up on a computer monitor in his office captures the evolutionary cat-and-mouse game his research lab is up against. The undulating curves track variants of the porcine reproductive ...
Molecular & Computational biology
Apr 13, 2026
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9
A specific protein controls mRNA transport in fungi and distinguishes important from unimportant binding sites in the transported mRNAs. Researchers from Würzburg and Düsseldorf have discovered this mechanism.
Cell & Microbiology
Apr 8, 2026
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10
Researchers at the Massachusetts Institute of Technology (MIT) have discovered thousands of new proteins that protect bacteria from virus attacks using an AI system called DefensePredictor. What would usually take months ...
In December, The Conversation hosted a webinar on AI's revolutionary role in drug discovery and development. Science and technology editor Eric Smalley interviewed Jeffrey Skolnick, eminent scholar in computational systems ...
Molecular & Computational biology
Apr 7, 2026
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19
A new tool makes it possible to screen millions of tiny protein fragments and select those that can be recognized by the immune system. The CIC biomaGUNE Center for Cooperative Research in Biomaterials has developed epiGPTope, ...
Biotechnology
Apr 7, 2026
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19
Ligand Pro, founded by Skoltech professors and a Skoltech Ph.D. student, has presented Matcha, an AI-powered molecular docking model that performs virtual drug screening 30 times faster than the large co-folding models of ...
Biotechnology
Apr 7, 2026
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7
Understanding how genes are switched on and off in specific cell types remains one of biology's central challenges. While AI has made major progress in decoding the regulatory logic of DNA, applying these approaches across ...
Biotechnology
Apr 2, 2026
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10
AI language models, used to generate human-like text to power chatbots and create content, are also revolutionizing biology by treating complex biological data like a language. Language models are increasingly used, for example, ...
Molecular & Computational biology
Apr 1, 2026
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