Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
Scientists at Université de Montréal's Institute for Research in Immunology and Cancer have developed a new database that integrates the molecular structure of microRNAs and messenger RNAs to systematically model their interactions. ...
Molecular & Computational biology
May 2, 2026
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How do our genes determine our appearance and our susceptibility to disease? This question is central to biomedical research, and today we can sequence thousands of human genomes to identify these genes. However, genes work ...
Cell & Microbiology
Apr 30, 2026
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49
Insilico Medicine, a clinical-stage biotechnology company powered by generative artificial intelligence (AI), today announced advancements to its unified AI framework for drug target discovery, integrating its previously ...
Biotechnology
Apr 29, 2026
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The genes that could help the world's crops survive drought, heat, and disease probably already exist. But much of this genetic diversity remains hidden within ancient plant varieties and forgotten seed collections, among ...
Molecular & Computational biology
Apr 28, 2026
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12
Researchers have developed a powerful new tool that can track how microbes spread between people with unprecedented precision, offering new ways to prevent infections and improve treatments in the future. The research, published ...
Cell & Microbiology
Apr 24, 2026
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10
Metagenomics relies on the use of software programs called assemblers, which can reconstruct tens of thousands of individual microbial genomes from DNA sequencing of samples such as soil, bodily fluids, or clinical swabs ...
Cell & Microbiology
Apr 22, 2026
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11
Although the genetic material of most living organisms is DNA, various self-replicating agents rely instead on RNA, including RNA viruses and viroids, which are infectious RNA molecules that are smaller and structurally simpler ...
Cell & Microbiology
Apr 21, 2026
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24
Researchers have developed a new artificial intelligence (AI) model that can more accurately predict how proteins interact with one another—an advancement that could accelerate drug discovery and deepen insights into diseases ...
Biotechnology
Apr 20, 2026
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36
Enzymes called proteases act like molecular scissors for proteins in the body and play a role in therapies to stop viruses from replicating and to kill cancer cells. The development of these medicines, however, has been slowed ...
Biotechnology
Apr 20, 2026
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10
Protein engineering is a field primed for artificial intelligence research. Each protein is made up of amino acids; to optimize a protein function, researchers modify proteins by switching out one of 20 different amino acids ...
Molecular & Computational biology
Apr 19, 2026
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